
脂肪原/USP30(人类)(记录)(His)/AG-40T-0554-C050/50µg
商品编号:
AG-40T-0554-C050
品牌:
Adipogen Inc
市场价:
¥11860.00
美元价:
7116.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | UbiquitinC-terminalHydrolase30;DeubiquitinatingEnzyme30;UbiquitinThioesterase30;Ubiquitin-specific-processingProtease30;EC3.1.2.15;EC3.4.19.12 |
ProductType | Protein |
Properties | |
Source/Host | Sf21cells |
Sequence | HumanUSP30(aa57-517)(AccessionNr.Q70CQ3)fusedtoaC-terminalHis-tag. |
Crossreactivity | Human |
MW | ~54kDa |
Purity | ≥98%(SDS-PAGE) |
Formulation | Liquid.In50mMHEPESpH7.2,400mMNaCl,10%Glycerol(v/v),2mMTCEP. |
OtherProductData | Use:Reactionconditionswillneedtobeoptimizedforeachspecificapplication.WerecommendaninitialUSP30concentrationof20-100nMinreactionsutilizingUbiquitin-AMCorUbiquitin-Rhodaminesubstrates,or200-500nMwhendigestingrecombinantpolyubiquitinchainsubstrates. |
Declaration | ManufacturedbyBostonBiochem |
ShippingandHandling | |
Shipping | DRYICE |
ShortTermStorage | -20°C |
LongTermStorage | -80°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
Ubiquitincarboxyl-terminalhydrolase30(USP30)isamemberoftheC19familyofpeptidasesandistetheredtotheoutermitochondrialsurfaceviaatrans-membranedomain.USP30activityisantagoNISTictothepro-mitophagysignalgeneratedbytheactivitiesofE3UbiquitinLigaseParkin(PARK2)andkinasePINK1,whicharestimulatedbymitochondrialdamage.Invivo,USP30cleavesUbiquitinfrommitochondrialsurfaceproteinssuchasMIRO1,TOMM20,MFN1andMFN2.TheenzymedisplaysastrongpreferenceforK6-andK11-linkedpolyubiquitinchainsinvitro,buthassubstantiallyloweractivityonpolyubiquitinchainsthathavebeenphosphorylatedwithPINK1kinase.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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