Apidogen/USP11（人类）（rec.）（His）/AG-40T-0558-C050/50µg
商品编号：
AG-40T-0558-C050
品牌：
Adipogen Inc
市场价：
¥8740.00
美元价：
5244.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | UbiquitinC-terminalHydrolase11;DeubiquitinatingEnzyme11;UbiquitinThioesterase11;Ubiquitin-specific-processingProtease11;TGT |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | HumanUSP11(AccessionNr.NP_004642.2). |
| Crossreactivity | Human |
| MW | ~110kDa |
| Purity | ≥85%(SDS-PAGE) |
| Formulation | Liquid.In50mMHEPES,pH7.5,100mMNaCl,10%glycerol,1mMTCEP. |
| OtherProductData | Use:Reactionconditionswillneedtobeoptimizedforeachspecificapplication.WerecommendaninitialrecombinanthumanUSP11concentrationof10-50nMwhenusingUbiquitin-AMC(AG-40T-0459)orUbiquitin-Rh110(AG-40T-0459RH)substrates. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Ubiquitincarboxyl-terminalhydrolase11(USP11)isaspecializedcysteineproteasewithapredictedmolecularweightof110kDa.USP11isamemberofthepeptidaseC19familyandthehumanproteinshares77%aminoacidsequenceidentitywithitsmouseortholog.USP11playsaroleinDNAdouble-strandbreak(DSB)repair,andcellsarehypersensitivetoγrADIationwhenUSP11hasbeenknockeddown.USP11overexpressionisoftenobservedincolorectalcancerandmelanomaandiscorrelatedwithpoorsurvival.InthesecasesUSP11maybedrivingdiseasestatesbystabilizingcIAP2.Interestingly,recentgeneticanalysissuggeststhatUSP11wasgeneratedduringthecourseofvertebrateevolutionbyasmall-scaleduplicationoftheUSP4-encodingregion.ThisrecombinantproteincontainsaC-terminal6-Histag.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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