(记录)(未标记)/SBB-CE0020-C100/100µg](https://www.ebiomall.cn/images/adipogen/sbb-ce0020_thioester-activity-web.png)
脂肪原/UBE2L3[UbcH7](人类)(记录)(未标记)/SBB-CE0020-C100/100µg
商品编号:
SBB-CE0020-C100
品牌:
Adipogen Inc
市场价:
¥3980.00
美元价:
2388.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Ubiquitin-conjugatingEnzymeE2L3;E2-F1;L-UBC;UBCE7;UbcM4;UBE2L3;Ubiquitin-proteinLigaseL3 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | HumanUBE2L3(aa1-154)(AccessionNr.P68036)isuntagged. |
Crossreactivity | Human |
Application | Typicalworkingconcentrationrangeis1-5µM. |
MW | ~18kDa |
Purity | ≥95%(SDS-PAGE) |
Concentration | Lotdependent. |
AccessionNumber | P68036 |
Formulation | Liquid.In50mMHEPESpH7.5,150mMsodiumchloride,10%glycerol,2mMTCEP. |
OtherProductData | ClickhereforaTypicalLot-specificProductDatasheetfromtheOriginalManufacturer Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
Declaration | ManufacturedbySouthBayBio. |
ShippingandHandling | |
Shipping | DRYICE |
ShortTermStorage | -80°C |
LongTermStorage | -80°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
UBE2L3(UbcH7)isanE2ubiquitinconjugatingenzymeandacceptsubiquitinfromanE1activatingenzymeviaanactivesitecysteine.ThemechanismofubiquitintransferinvolvesthebreakingofaE1-Ubthioesterlinkage,followedbyareformationofaUBE2L3-Ubthioester.UBE2L3transfersactiveubiquitinmoleculesviaafinaltransthiolationreactiontoacysteineresidueofHECTclassorRBRclassE3ligases.UBE2L3playsacriticalroleintheactivationofNF-κbsignalingbyworkinginconjugationwiththeRBRE3ligase,LUBAC(linearubiquitinassemblycomplex),toubiquitinateNEMOoftheIκBcomplex,whichthanfacilitatesthedownstreamimmuneresponse.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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