脂肪原/UBE2F（人类）（记录）（His）/AG-40T-0435-C100/100µg
商品编号：
AG-40T-0435-C100
品牌：
Adipogen Inc
市场价：
¥7440.00
美元价：
4464.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Ubiquitin-conjugatingEnzymeE2F;NCE2;NEDD8-conjugatingEnzymeUBE2F;NEDD8ProteinLigaseUBE2F |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | HumanUBE2F(AccessionNr.NP_542409)fusedtoaN-terminalHis-tag. |
| Crossreactivity | Human |
| Formulation | Liquid.In50mMHEPESpH7.5,200mMNaCl,10%Glycerol(v/v),1mMTCEP. |
| OtherProductData | Use:MemberoftheNEDD8-conjugating(E2)enzymefamilythatreceivesNEDD8fromaNEDD8-activating(E1)enzymeandsubsequentlyinteractswithaNEDD8ligase(E3)toconjugateNEDD8tosubstrateproteins.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof0.1-1μM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Ubiquitin-conjugatingEnzymeE2F(UBE2F)isaNEDD8-conjugatingenzyme(E2).Itisa185aminoacid(aa)proteinwithapredictedmolecularweightof21kDa.Thehumanproteinexhibitsapproximately96%aasequenceidentitywithitsmouseandratorthologs.UBE2FisinvolvedthecovalentattachmentofNEDD8totargetproteinsinaprocesstermedneddylation.Forexample,UBE2FappearstoparticipateintheneddyylationofCullin5.MembersoftheCullinfamily(Cullin1-7)arescaffoldproteinsthatcanincorporateintomultimolecularcomplexestermedCullinRINGubiquitinLigases(CRLs).CRLsmakeupthelargestsubsetofubiquitinligases(E3),andtheiractivityispromotedbyneddylationofassociatedCullinfamilyproteins.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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