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Adipogen/UBE2D1 [UbcH5a] (human) (rec.) (untagged)/SBB-CE0021-C100/100 µg
![Adipogen/UBE2D1 [UbcH5a] (human) (rec.) (untagged)/SBB-CE0021-C100/100 µg](https://www.ebiomall.cn/images/adipogen/sbb-ce0021_thioester-activity-web.png)
Adipogen/UBE2D1 [UbcH5a] (human) (rec.) (untagged)/SBB-CE0021-C100/100 µg
商品编号：
SBB-CE0021-C100
品牌：
Adipogen Inc
市场价：
¥3980.00
美元价：
2388.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Ubiquitin-conjugating Enzyme H5a; PUBC1; UBC5A; Ubiquitin-protein Ligase D1; p53-regulated Ubiquitin-conjugating Enzyme 1 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Human UBE2D1 (aa1-147) (Accession Nr. P51668) is untagged. |
| Crossreactivity | Human |
| Application | Typical working concentration range is 1-5µM. |
| MW | ~17kDa |
| Purity | ≥95% (SDS-PAGE) |
| Concentration | Lot dependent. |
| Accession Number | P51668 |
| Formulation | Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol (v/v), 2mM TCEP. |
| Other Product Data |
Click here for a Typical Lot-specific Product Datasheet from the Original Manufacturer Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by South Bay Bio. |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -80°C |
| Long Term Storage | -80°C |
| Handling Advice | Aliquot to avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -80°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of associating with numerous known E3 ligases which target abnormal proteins for proteasomal degradation through polyubiquitination. UBE2D1 is also known to interact with Parkin and to be involved in PINK1 mediated mitophagy.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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