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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/UbcH2 (human) (rec.) (GST)/AG-40T-0416-C100/100 µg
商品详细Adipogen/UbcH2 (human) (rec.) (GST)/AG-40T-0416-C100/100 µg
Adipogen/UbcH2 (human) (rec.) (GST)/AG-40T-0416-C100/100 µg
Adipogen/UbcH2 (human) (rec.) (GST)/AG-40T-0416-C100/100 µg
商品编号: AG-40T-0416-C100
品牌: Adipogen Inc
市场价: ¥7440.00
美元价: 4464.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsUbiquitin-conjugatingEnzymeE2H;E2-14K;E2-20K;UBC8;UBE2H;Ubiquitin-proteinLigaseH
ProductTypeProtein
Properties
Source/HostE.coli
SequenceHumanUbcH2(AccessionNr.NP_003335)fusedtoaN-terminalGST-tag.
CrossreactivityHuman
FormulationLiquid.In50mMHEPES,pH8.0,100mMNaCl,and10%Glycerol
OtherProductDataUse:Memberoftheubiquitin­conjugating(E2)enzymefamilythatreceivesubiquitinfromaubiquitin­activating(E1)enzymeandsubsequentlyinteractswithaubiquitinligase(E3)toconjugateubiquitintosubstrateproteins.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof0.1-­1μM.
DeclarationManufacturedbyBostonBiochem
ShippingandHandling
ShippingDRYICE
ShortTermStorage-20°C
LongTermStorage-80°C
HandlingAdviceAliquottoavoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-80°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Ubiquitin-conjugatingEnzymeH2(UbcH2),alsoknownasubiquitin-conjugatingEnzymeE2H(UBE2H),isamemberoftheubiquitin-conjugating(E2)enzymefamily.UbcH2/UBE2Hhasapredictedmolecularweightof20.5kDa.Thehumanproteinshares100%aminoacidsequenceidentitywiththemouseandratorthologs.HumanUbcH2/UBE2Hishighlyexpressedinskeletalandcardiacmuscle,showssignificantexpressionlevelsinkidneyandplacenta,andisexpressedatlowlevelsinliver,brain,lung,andspleen.TNF-αinducesUbcH2/UBE2HexpressionviaNF-κB,andSCL/Tal1upregulatestheexpressionofUbcH2/UBE2Hduringerythroiddifferentiation.Pathologically,asinglenucleotidepolymorphismwithinUbcH2/UBE2Hisassociatedwithautism.FurThermore,UbcH2/UBE2HhasbeenreportedasaputativeoncogeneforlivertumOrigenesis.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。