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Adipogen/TNF-R1 (human):Fc (human) (rec.)/AG-40B-0074-C050/50 µg
Adipogen/TNF-R1 (human):Fc (human) (rec.)/AG-40B-0074-C050/50 µg
商品编号：
AG-40B-0074-C050
品牌：
Adipogen Inc
市场价：
¥3600.00
美元价：
2160.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | p55; CD120a; TNFRSF 1A; Tumor Necrosis Factor Receptor Superfamily Member 1A; TNF Receptor 1 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | The extracellular domain of human TNF-R1 (aa 22-211) is fused to the Fc portion of human IgG1. |
| Crossreactivity |
Human Mouse |
| Specificity | Binds human and mouse TNF-α. |
| Biological Activity | TNF-R1:Fc fusion protein blocks TNF-α-mediated biological effect with an inhibitory activity in a concentration range of 0.1 to 1μg/ml. |
| MW | ~60kDa (reducing SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 50μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | UniProt link P19438: TNF-R1 (human) (precursor) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
TNF-R1 is a receptor for TNF-α and homotrimeric lymphotoxin-α. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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