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Adipogen/Tim-1 (mouse):Fc (human) (rec.)/CHI-MF-111T1-C100/100 µg
Adipogen/Tim-1 (mouse):Fc (human) (rec.)/CHI-MF-111T1-C100/100 µg
商品编号：
CHI-MF-111T1-C100
品牌：
Adipogen Inc
市场价：
¥7800.00
美元价：
4680.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | TIM1; KIM1; TIMD1; Hepatitis A Virus Cellular Receptor 1; HAVcr-1; T Cell Immunoglobulin and Mucin Domain-containing Protein 1; T Cell Membrane Protein 1 |
| Product Type | Protein |
| Properties | |
| Source/Host | CHO cells |
| Sequence | The extracellular domain of mouse Tim-1 (aa 22-212) is fused to the N-terminus of the Fc region of human IgG1. |
| Crossreactivity | Mouse |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | <0.06eu mu;g="" protein="" (lal="" test;="" lonza).=""> |
| Reconstitution | Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration. |
| Formulation | Lyophilized from 0.2μm-filtered solution in PBS. |
| Other Product Data | NCBI reference NP_001160104.1: Tim-1 (mouse) |
| Declaration | Manufactured by Chimerigen. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-1 (KIM-1; HAVcr-1) is a 100 kDa, type I transmembrane glycoprotein member of the TIM family of immunoglobulin superfamily molecules. There are two cytoplasmic alternate splice forms of Tim-1. One is a long (359 aa) kidney form termed Tim-1b, and one is a short (334 aa) liver form termed Tim-1a. Tim-1, important for asthma and allergy, is preferentially expressed on T-helper 2 (Th2) cells and functions as a potent costimulatory molecule for T cell activation.
Product References
- TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation: J.H. Meyers, et al.; J. Immunol. 6, 455 (2005)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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