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Adipogen/Thioredoxin Reductase 1 SelCys498Cys (human) (rec.)/YIF-LF-P0021/0.5 mg
Adipogen/Thioredoxin Reductase 1 SelCys498Cys (human) (rec.)/YIF-LF-P0021/0.5 mg
商品编号：
YIF-LF-P0021
品牌：
Adipogen Inc
市场价：
¥6400.00
美元价：
3840.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | TR;TXNRD1;GRIM12;GRIM-12;EC=1.8.1.9;ThioredoxinReductaseTR1;KM-102-derivedReductase-likeFactor;ThioredoxinReductase1;Cytoplasmic;GeneAssociatedwithRetinoicandIFN-inducedMortality12Protein |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Crossreactivity | Human |
| Purity | ≥95%(SDS-PAGE) |
| Formulation | Lyophilizedfrom20mMHEPES,pH7.0,1mMEDTA. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Afterreconstitution,storeat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Themammalianthioredoxinreductases(TrxRs)areafamilyofselenocysteine-containingpyridinenucleotide-disulfideoxido-reductases.AllthemammalianTrxRsarehomologoustoglutathionereductasewithrespecttoprimarystructureincludingtheconservedredoxcatalyticsite(-Cys-Val-Asn-Val-Gly-Cys-)butdistinctivelywithaC-terminalextensioncontainingacatalyticallyactivepenultimateselenocysteine(SeCys)residueintheconservedsequence(-Gly-Cys-SeCys-Gly).TrxRishomodimericproteininwhicheachmonomerincludesanFADprostheticgroup,aNADPHbindingsiteandaredoxcatalyticsite.ElectronsaretransferredfromNADPHviaFADandtheactive-sitedisulfidetoC-terminalSeCys-containingredoxcenter,whichthenreducesthesubstratelikethioredoxin.ThemembersofTrxRfamilyare55–58kilodaltoninmolecularsizeandcomposedofthreeisoformsincludingcytosolicTrxR1,mitochondrialTrxR2,andTrxR3,knownasTrxandGSSGreductase(TGR).TrxRplaysakeyroleinprotectionofcellsagainstoxidativestressandredox-regulatorymechanismoftranscriptionfactorsandvariousBIOLOGicalphenomena(1).
ProductReferences
1)Mustacich,D.andPowis,G.(2000)BiochemJ.15.346Pt1:1-8.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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