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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/Tetra-ubiquitin [Ub4] WT Chains (K63-linked) (human) (rec.) (Biotin)/AG-40T-0399B-C025/25 µg
商品详细Adipogen/Tetra-ubiquitin [Ub4] WT Chains (K63-linked) (human) (rec.) (Biotin)/AG-40T-0399B-C025/25 µg
Adipogen/Tetra-ubiquitin [Ub4] WT Chains (K63-linked) (human) (rec.) (Biotin)/AG-40T-0399B-C025/25 µg
Adipogen/Tetra-ubiquitin [Ub4] WT Chains (K63-linked) (human) (rec.) (Biotin)/AG-40T-0399B-C025/25 µg
商品编号: AG-40T-0399B-C025
品牌: Adipogen Inc
市场价: ¥4840.00
美元价: 2904.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
ProductTypeProtein
Properties
Source/HostE.coli
SequenceFourhumanubiquitin(AccessionNr.P0CG47)covalentlylinkedthroughisopeptidebondsatK63residuesofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmoleculeandconjugatedtobiotin.
CrossreactivityHuman
Label/ConjugatesBiotin
FormulationLyophilizedfromasolutionindeionizedwater.
OtherProductDataUse:Formedwithwild-typehumanrecombinantubiquitinandlinkage-specificenzymes.Modifiedwithbiotinviaprimaryaminecoupling.ThisresultsinmultiplebiotinylatedspeciesmodifiedattheN-terminus,aswellaslysineresidues.Biotinylatedubiquitincanbedetectedusingavidin-linkedreagents.Linkage-specifictetra-ubiquitincanbeusedtoinvestigatemechanismofbindingandrecognitionbyE1orE2enzymes,deubiquitinatingenzymes,E3ligasesorotherproteinsthatcontainubiquitin-associateddomainsorubiquitin-interactingmotifs(UIMs).Idealforinvestigatingubiquitin-bindingproteinsandassubstratesforubiquitin-specificisopeptidases.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.

IMPORTANT:HeatingthisproductinSDS-PAGEbufferorterminatingreactionscontainingthisproductwithheatedSDS-PAGEbuffercouldleadtounexpected,highapparentmolecularweightbandingorsmearingongelsthatisnotrepresentativeofproductpurity.Foroptimalresults,werecommendincubationinSDS-PAGEbuffer+DTTat<40°c for="" 20="" minutes="" prior="" to="" gel="" electrophoresis.="">
DeclarationManufacturedbyBostonBiochem
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAliquottoavoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Withapredictedmolecularweightof34kDa,Tetra-ubiquitinchainsarecomposedoffourubiquitinmonomersthatarecovalentlylinkedthroughisopeptidebonds,whichtypicallyformbetweenalysineresidueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule.Eachhumanubiquitinmonomeris76aminoacids(aa)inlengthandshares96%and100%aaidentitywithyeastandmouseubiquitin,respectively.Sevenofthe76aainubiquitinarelysineresiduesthatcanparticipateinpoly-ubiquitinchainformation.Linkagethroughspecificlysineresiduesisthoughttoserveasasignalthataffectsproteindegradation,signaling,traffickingandothercellularprocesses.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。