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Adipogen/Tetra-ubiquitin [Ub4] Non-hydrolyzable (K48-linked) (human) (rec.) (Agarose)/AG-40T-0391-R100/100 µl
![Adipogen/Tetra-ubiquitin [Ub4] Non-hydrolyzable (K48-linked) (human) (rec.) (Agarose)/AG-40T-0391-R100/100 µl](https://www.ebiomall.cn/images/adipogen/adipogen_logo_bw_2.png){kind=logo}
Adipogen/Tetra-ubiquitin [Ub4] Non-hydrolyzable (K48-linked) (human) (rec.) (Agarose)/AG-40T-0391-R100/100 µl
商品编号：
AG-40T-0391-R100
品牌：
Adipogen Inc
市场价：
¥6340.00
美元价：
3804.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | FourhumanubiquitinL73Pmutants(AccessionNr.P0CG47)covalentlylinkedthroughisopeptidebondsatK48residuesofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule,andcoupledtoagarose. |
| Crossreactivity | Human |
| Label/Conjugates | Agarose |
| MW | ~34kDa |
| Formulation | Liquid.In20%Ethanol. |
| OtherProductData | Use:Linkage-specific,non-hydrolyzabletetra-ubiquitinisresistanttotheactivityofdeubiquitinatingenzymes(DUB"s)thatcleavetheisopeptidelinkagebetweenadjacentubiquitinmolecules.Maybeusefulforinvestigatingubiquitin-bindingproteinsandexploringtheroleofunanchored(freeC-terminus)ubiquitinchainsinsignalingpathways.Tetra-ubiquitinistheminimalunitnecessaryforrecognitionbythe26SProteasomeandcontainsstructuralcharacteristics(suchasrepeatinghydrophobicpatches)notpresentindi-ubiquitin.Usefulfortheenrichmentofknownubiquitinchain-interactingproteinsaswellasthediscoveryofnovelubiquitinchain-interactingproteins.Werecommendequilibratingtheresinbywashingwith10volumesofyourdesiredaqueousbuffer. Storage:Polyubiquitin-agarosecanbere-usedifproperlymaintained.Afteruse,cleanresinwithawashcycleof5volumes100mMHEPESpH8.0,500mMNaClfollowedby5volumes100mMNaOAcpH4.5,500mMNaCl.Repeattwice,thenrinseresinwithalowsaltbuffer.Storeresinat4°Cinneutralaqueousbuffercontaining1mMNaN3or20%ethanolasapreservative. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Donotfreeze. |
| Use/StABIlity | Stableforatleast3monthsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Withapredictedmolecularweightof34kDa,Tetra-ubiquitinchainsarecomposedoffourubiquitinmonomersthatarecovalentlylinkedthroughisopeptidebonds,whichtypicallyformbetweenalysineresidueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule.Eachhumanubiquitinmonomeris76aminoacids(aa)inlengthandshares96%and100%aaidentitywithyeastandmouseubiquitin,respectively.Sevenofthe76aainubiquitinarelysineresiduesthatcanparticipateinpoly-ubiquitinchainformation.Linkagethroughspecificlysineresiduesisthoughttoserveasasignalthataffectsproteindegradation,signaling,trafficking,andothercellularprocesses.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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