
脂肪原/Sumo1(小泛素相关修饰物)(人类)(推荐)/YIF-LF-P0326/0.5 mg
商品编号:
YIF-LF-P0326
品牌:
Adipogen Inc
市场价:
¥7000.00
美元价:
4200.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | GMP1;SMT3C;SUMO1;Smt3C;SUMO-1;Sentrin;SMT3Homolog3;GAP-modifyingProtein1;Ubiquitin-likeProteinUBL1;Ubiquitin-likeProteinSMT3C;SmallUbiquitin-relatedModifier1;Ubiquitin-HomologyDomainProteinPIC1 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Crossreactivity | Human |
Purity | ≥95%(SDS-PAGE) |
Formulation | Lyophilizedfrom20mMTris,pH8.0/10mMNaCl. |
OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
Declaration | ManufacturedbyAbFrontier |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Avoidfreeze/thawcycles. |
Use/StABIlity | Afterreconstitution,storeat-80°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
Thesmallubiquitin-relatedmodifier(SUMO)belongstothegrowingfamilyofubiquitin-relatedproteinsinvolvedinposttranslationalproteinmodification.Itispresentinalleukaryotickingdomsandishighlyconservedfromyeasttohumans.TheSUMOfamilyarecomposedofthreetypes;SUMO1,SUMO2andSUMO3.Likeubiquitin,SUMO1isconjugatedtotargetproteinsbyanenzymaticcascadeinvolvingE1,E2enzymeandE3lygase(knownassumoylation).IthasbeenknownthatmanysubstratessuchasRanGAP1,PMLandIkBaproteinsarepresentincells.Incontrasttoubiquitination,sumoylationdoesnottagproteinsfordegradationbythe26Sproteosome.Sumoylationparticipatesindiverseeventssuchasnucleartransport,transcriptionalregulation,chromosomesegregationandcellcyclecontrol.Alsothemodificationisassociatedwithpathologicalconditions(neurodegeneration,diabetesandInflammation).
ProductReferences
1)MullerS.etal.,(2001)NatRevMolCellBiol.2:202-210.(General)
2)GillG,(2004)GenesDev.18(17):2046-2059.(General)
3)HayRT,(2005)MolCell.18(1):1-12.(General)
4)DegernyCetal.,(2005)JBiolChem.280(26):24330-24338.(General)
2)GillG,(2004)GenesDev.18(17):2046-2059.(General)
3)HayRT,(2005)MolCell.18(1):1-12.(General)
4)DegernyCetal.,(2005)JBiolChem.280(26):24330-24338.(General)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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