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Adipogen/Semaphorin-4A (mouse):Fc (human) (rec.)/CHI-MF-111SEMA4-C100/100 µg
Adipogen/Semaphorin-4A (mouse):Fc (human) (rec.)/CHI-MF-111SEMA4-C100/100 µg
商品编号:
CHI-MF-111SEMA4-C100
品牌:
Adipogen Inc
市场价:
¥7600.00
美元价:
4560.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Sema4a;Semaphorin-B;SemaB |
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Sequence | TheextracellulardomainofmouseSemaphorin-4A(aa1-676)isfusedtotheN-terminusoftheFcregionofhumanIgG1. |
| Crossreactivity | Mouse |
| Purity | ≥98%(SDS-PAGE) |
| EndotoxinContent | <0.06eu mu;g="" protein="" (lal="" test;="" lonza).="">0.06eu> |
| Reconstitution | Reconstituteat100μg/mlinsterilePBS. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceNP_038686.3:Semaphorin-4A(mouse) |
| Declaration | ManufacturedbyChimerigen. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Semaphorin4A(Sema4A,previouslysemB)isaClass4transmembraneSemaphorinwithactivityintheimmuneandnervoussystems.Sema4AwasfirstdescribedasamoleculethatenhancesTcellactivationandinteractswithTIM2(Tcellimmunoglobulinandmucindomain2).MicewithtargeteddisruptionofSema4AshowdefectsindendriticcellmediatedTcellprimingandTh1responses.RolesforSema4Ahavealsobeenidentifiedinthebrain,theendotheliumandtheeye.ItmediateshippocampalneurongrowthconecollapseinvitrothroughinteractionofthesemadomainwithplexinB1.InteractionofSema4AwithendothelialcellplexinD1causesoppositiontotheangiogenic,proliferative,chemotacticandintegrinmediatedadhesiveactionsofVEGF.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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