
脂肪原/抵抗素(人类)(推荐)/AG-40A-0010Y-C010/10µg
商品编号:
AG-40A-0010Y-C010
品牌:
Adipogen Inc
市场价:
¥4400.00
美元价:
2640.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Details | |
---|---|
Synonyms | FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor |
Product Type | Protein |
Properties | |
Source/Host | HEK 293 cells |
Sequence | Human resistin (aa 19-108) is fused at the N-terminus to a FLAG®-tag. |
Crossreactivity | Human |
Biological Activity | Inhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells. |
MW | ~13kDa (SDS-PAGE) |
Purity | ≥95% (SDS-PAGE) |
Endotoxin Content | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu> |
Concentration |
After reconstitution: for 10µg size: 0.1mg/ml for 50µg size: 1 mg/ml |
Reconstitution |
10µg size: Reconstitute with 100µl sterile water. 50µg size: Reconstitute with 50µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions. |
Formulation | Lyophilized. Contains PBS. |
Other Product Data |
UniProt link Q9HD89: Resistin (human) (precursor) FLAG is a registered trademark of Sigma-Aldrich Co. |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-α/FIZZ 1 and RELM-β/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Product References
Expression of resistin in the prostate and its stimulatory effect on prostate cancer cell proliferation: H.J. Kim, et al.; BJU Int. 108: 1464 (2010)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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