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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/Pro-UFM1 (human) (rec.) (His)/AG-40T-0347-C250/250 µg
商品详细Adipogen/Pro-UFM1 (human) (rec.) (His)/AG-40T-0347-C250/250 µg
Adipogen/Pro-UFM1 (human) (rec.) (His)/AG-40T-0347-C250/250 µg
Adipogen/Pro-UFM1 (human) (rec.) (His)/AG-40T-0347-C250/250 µg
商品编号: AG-40T-0347-C250
品牌: Adipogen Inc
市场价: ¥5160.00
美元价: 3096.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsUbiquitin-foldModifier1;C13orf20
ProductTypeProtein
Properties
Source/HostE.coli
SequenceHumanPro-UFM1(AccessionNr.NP_057701)fusedtoaN-terminalHis-tag.
CrossreactivityHuman
FormulationLiquid.InHEPES,NaCl,DTTandGlycerol.
OtherProductDataUse:CanbeconjugatedtosubstrateproteinsviathesubsequentactionsofaUFM1-activating(E1)enzyme,aUFM1-conjugating(E2)enzyme,andaUFM1ligase(E3).Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof10-50µM.
DeclarationManufacturedbyBostonBiochem
ShippingandHandling
ShippingDRYICE
ShortTermStorage-20°C
LongTermStorage-80°C
HandlingAdviceAliquottoavoidfreeze/thawcycles.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-80°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Ubiquitin-foldModifier1(UFM1),alsoknownasBM-002,isan85aminoacid(aa)memberoftheubiquitin-likeproteinfamilythathasapredictedmolecularweightof9.1kDa.HumanandmouseUFM1share100%aasequenceidentityandareprimarilylocalizedinthenucleus,butcanalsobedetectedinthecytoplasmandtheendoplasmicreticulum(ER).ERlocalizationofUFM1appearstobedependentontheco-expressionofUFBP1.Initiallyexpressedasaninactiveprecursor,UFM1undergoesproteolyticcleavageattheC-terminustoexposeaconservedglycineresiduethatisnecessaryforUFM1conjugationtotargetproteins.ConjugationofUFM1totargetproteinsrequiresaUFM1-activating(E1)enzyme,aUFM1-conjugating(E2)enzymeandaUFM1ligase(E3).UFM1hasbeenshowntobeamediatorofERstress-inducedcancerandtopromotethepathogenesisofLeishmania.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。