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Adipogen/Poly-SUMO3 Wild-type Chains (2-8) (human) (rec.)/AG-40T-0324-C025/25 µg
Adipogen/Poly-SUMO3 Wild-type Chains (2-8) (human) (rec.)/AG-40T-0324-C025/25 µg
商品编号：
AG-40T-0324-C025
品牌：
Adipogen Inc
市场价：
¥5160.00
美元价：
3096.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | SmallUbiquitin-relatedModifier3;HSMT3;SMT3Homolog1;Ubiquitin-likeProteinSMT3B |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | 2-8humanSUMO3(AccessionNr.P0CG47)covalentlylinkedthroughanisopeptidebondatK11residueofoneSUMO3moleculeandtheC-terminalglycineresidueofanotherSUMO3molecule. |
| Crossreactivity | Human |
| Formulation | Liquid.InHEPES,NaClandDTT. |
| OtherProductData | Use:FormedenzymaticallywithwildtypehumanrecombinantSUMO-3linkedvialysine11whichisthepointofattachmentfortheC-terminalglycineoftheprecedingSUMO-3.Mono-SUMO-3hasbeenremovedfromthechainmixture.IdealforinvestigatingSUMO-bindingproteinsandassubstratesforSUMO-specificproteases.Typicalconcentrationswilldependonspecificassayconditionsandmethodofdetection. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
SmallUbiquitin-likeModifier3(SUMO3),alsoknownasSMT3A,issynthesizedasa103aminoacid(aa),propeptidewithapredicted11.5kDa.SUMO3containsatwoaaC-terminalprosegment.HumanSUMO3shares83%sequenceidentitywithmouseSUMO3.Di-SUMO3representstwowild-typerecombinanthumanSUMO3moleculeslinkedviaLys11,whichisthepointofattachmentfortheC-terminalglycineresidueoftheprecedingSUMO3.Di-SUMO3canbeusedasasubstrateforSUMO-specificisopeptidases(SENPs)andDeSUMOylatingIsopeptidase1thatcleavetheisopeptidelinkagebetweentwoadjacentSUMO3molecules.Di-SUMO3canalsobeusedtoinvestigatemechanismsofbindingandrecognitionbySUMO-activating(E1)enzymes,SUMO-conjugating(E2)enzymes,SUMOE3ligasesandotherproteinsthatcontainSUMObindingdomains.SUMOsareafamilyofsmall,relatedproteinsthatcanbeenzymaticallyattachedtoatargetproteinbyapost-translationalmodificationprocesstermedSUMOylation.UnlikeSUMO1whichisusuallyconjugatedtoproteinsasamonomer,SUMO2andSUMO3formhighmolecularweightpolymersonproteins.AllSUMOproteinsshareaconservedubiquitindomainandaC-terminaldiglycinecleavage/attachmentsite.Followingprosegmentcleavage,theC-terminalglycineresidueofSUMO3isenzymaticallyattachedtoalysineresidueonatargetprotein.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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