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Adipogen/PARP-3 [ARTD3] (human) (rec.) (His) (high purity)/AG-40T-0013-C010/10 µg
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Adipogen/PARP-3 [ARTD3] (human) (rec.) (His) (high purity)/AG-40T-0013-C010/10 µg
商品编号：
AG-40T-0013-C010
品牌：
Adipogen Inc
市场价：
¥5200.00
美元价：
3120.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Poly(ADP-ribose)Polymerase3;ADP-ribosyltransferaseDiphtheriaToxin-like3;NAD(+)ADP-ribosyltransferase3 |
| ProductType | Protein |
| Properties | |
| Source/Host | Sf21cells |
| Sequence | Humanfull-lengthPARP-3[ARTD3]isfusedtoaHA-tagandaHis-tag. |
| Crossreactivity | Human |
| BIOLOGicalActivity | ≥10U/mgprotein(onlymonoADP-ribosyltransferaseactivity). |
| Purity | ≥98%(SDS-PAGE) |
| Concentration | Lotdependent(0.2-1mg/ml) |
| Formulation | Liquid.In50mMTRIS-HCl,pH7.5,containing100mMsodiumchlorideand50mMimidazole,0.2%NP-40and10%glycerol. |
| OtherProductData | UniProtIDQ9Y6F1:PARP-3(human) |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-80°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
PARP-3[ARTD3]isinvolvedinthebaseexcisionrepair(BER)pathway,bycatalyzingthepoly(ADP-ribosyl)ationofalimitednumberofacceptorproteinsinvolvedinchromatinarchitectureandinDNAmetabolism.ThismodificationfollowsDNAdamagesandappearsasanobligatorystepinadetection/signalingpathwayleADIngtothereparationofDNAstrandbreaks.MaylinktheDNAdamagesurveillancenetworktothemitoticfidelitycheckpoint.NegativelyinfluencestheG1/Scellcycleprogressionwithoutinterferingwithcentrosomeduplication.MaybeinvolvedintheregulationofPRC2andPRC3complex-dependentgenesilencing.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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