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Adipogen/Nampt (Visfatin/PBEF) (rat) (rec.)/AG-40A-0058-C010/10 µg
Adipogen/Nampt (Visfatin/PBEF) (rat) (rec.)/AG-40A-0058-C010/10 µg
商品编号：
AG-40A-0058-C010
品牌：
Adipogen Inc
市场价：
¥3400.00
美元价：
2040.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Pre-BCellColonyEnhancingFactor1;PBEF1;NicotinamidePhosphoribosyltransferase |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | RatNampt(visfatin/PBEF)(aa1-491)isfusedattheN-terminustoaFLAG®-tag. |
| Crossreactivity | Rat |
| MW | ~60kDa(SDS-PAGE) |
| Purity | ≥90%(SDS-PAGE) |
| EndotoxinContent | <0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.35mg/ml |
| Formulation | Liquid.0.2μm-filteredsolutioninPBS,pH7.2. |
| OtherProductData | UniProtlinkQ80Z29:Nicotinamidephosphoribosyltransferase(rat) FLAGisaregisteredtrademarkofSigma-AldrichCo. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Formaximumproductrecoveryafterthawing,centrifugethevialbeforeopeningthecap. |
| Use/StABIlity | Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Nicotinamidephosphoribosyltransferase(Nampt;pre-Bcellcolony-enhancingfactor;PBEF;Visfatin)isan52kDaADIpokinesecretedbyadiposetissueandinvolvedinthebiosynthesisofnicotinamideadeninedinucleotide(NAD+).TwoformsofNamptexist,anintracellularform(iNampt)andanextracellularform(eNampt).WhilethefunctionofiNamptasanessentialandrate-limitingNAD+biosyntheticenzymeiswellestablished,thephysiologicalroleofeNamptisstillamatterofdebate.Nampthasvariousfunctions,includingthepromotionofvascularsmoothmusclecellmaturationandinhibitionofneutrophilapoptosis.Itactivatesinsulinreceptorandhasinsulin-mimeticeffects,loweringbloodglucoseandimprovinginsulinsensitivity.Theproteinishighlyexpressedinvisceralfatandserumlevelsoftheproteincorrelatewithobesity.
ProductReferences
- TheadipocytokineNamptanditsproductNMNhavenoeffectonbeta-cellsurvivalbutpotentiateglucosestimulatedinsulinsecretion:R.Spinnler,etal.PLoSOne8,e54106(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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