当前位置：
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/Nampt (Visfatin/PBEF) (human) (rec.) (His)/AG-40A-0018-C050/50 µg
Adipogen/Nampt (Visfatin/PBEF) (human) (rec.) (His)/AG-40A-0018-C050/50 µg
商品编号：
AG-40A-0018-C050
品牌：
Adipogen Inc
市场价：
¥7000.00
美元价：
4200.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Pre-BCellColonyEnhancingFactor1;PBEF1;NicotinamidePhosphoribosyltransferase |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | IntracellularhumanNampt(visfatin/PBEF)(aa1-491)isfusedattheC-terminustoaHis-tag. |
| Crossreactivity | Human |
| BIOLOGicalActivity | ShowsADIpogeniceffectsinstimulateddifferentiating3T3-L1cells. |
| MW | ~52kDa(SDS-PAGE) |
| Purity | ≥90%(SDS-PAGE) |
| EndotoxinContent | <1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Reconstitution | Reconstituteindistilledwater. |
| Formulation | Lyophilized.Salt-free. |
| OtherProductData | UniProtlinkP43490:Nicotinamidephosphoribosyltransferase(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Formaximumproductrecoveryafterthawing,centrifugethevialbeforeopeningthecap. |
| Use/StABIlity | Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Nicotinamidephosphoribosyltransferase(Nampt;pre-Bcellcolony-enhancingfactor;PBEF;Visfatin)isan52kDaadipokinesecretedbyadiposetissueandinvolvedinthebiosynthesisofnicotinamideadeninedinucleotide(NAD+).TwoformsofNamptexist,anintracellularform(iNampt)andanextracellularform(eNampt).WhilethefunctionofiNamptasanessentialandrate-limitingNAD+biosyntheticenzymeiswellestablished,thephysiologicalroleofeNamptisstillamatterofdebate.Nampthasvariousfunctions,includingthepromotionofvascularsmoothmusclecellmaturationandinhibitionofneutrophilapoptosis.Itactivatesinsulinreceptorandhasinsulin-mimeticeffects,loweringbloodglucoseandimprovinginsulinsensitivity.Theproteinishighlyexpressedinvisceralfatandserumlevelsoftheproteincorrelatewithobesity.
ProductReferences
- Visfatinispresentinbovinemammaryepithelialcells,lactatingmammaryglandandmilk,anditsexpressionisregulatedbycAMPpathway:T.Yonezawa,etal.;FEBSLett.580,6635(2006)
- Molecularcharacteristicsofserumvisfatinanddifferentialdetectionbyimmunoassays:A.Körner,etal.;J.Clin.Endocrinol.Metab.92,4783(2007)Lackofdirectinsulin-likeactionofvisfatin/Nampt/PBEF1inhumanadipocytes:E.Wanecq,etal.;J.Physiol.Biochem.65,351(2009)
- Expressionandregulationofnamptinhumanislets:K.Kover,etal.;PLoSOne8,e58767(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
