脂肪原/NAD合成酶（B。枯草杆菌（rec.）/AG-40T-0109-C050/50µg
商品编号：
AG-40T-0109-C050
品牌：
Adipogen Inc
市场价：
¥7800.00
美元价：
4680.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | NH(3)-dependent NAD(+) Synthetase; General Stress Protein 38; GSP38; Spore Outgrowth Factor B; EC6.3.1.5 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Full-length NAD synthetase (Bacillus subtilis). |
| Biological Activity | ~0.3 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1µmol NAD per min. |
| MW | ~30.4kDa |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | N/A |
| Concentration | 0.5mg/ml (Lot specific) |
| Formulation | Liquid. In 50mM TRIS-HCl, pH 8, containing 75mM sodium chloride, 5% glycerol and 5mM DTT. |
| Other Product Data | UniProt link P08164: NAD Synthetase (B. subtilis) |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -80°C |
| Handling Advice |
After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -80°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It was shown to be induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation and is involved in biological processes like stress response and sporulation resulting in formation of a cellular spore.
Catalytic activity: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+
Catalytic activity: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+
Product References
- Crystal structure of NH3-dependent NAD+ synthetase from Bacillus subtilis: M. Rizzi, et al.; EMBO J. 15, 5125 (1996)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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