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Adipogen/NAD Kinase (M. tuberculosis) (rec.) (His)/AG-40T-0107-C050/50 µg
Adipogen/NAD Kinase (M. tuberculosis) (rec.) (His)/AG-40T-0107-C050/50 µg
商品编号：
AG-40T-0107-C050
品牌：
Adipogen Inc
市场价：
¥6400.00
美元价：
3840.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ProbableInorganicPolyphosphate/ATP-NADkinase;Poly(P)/ATPNADKinase1;ppnK1;EC2.7.1.23 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | NADkinase(Mycobacteriumtuberculosis)isfusedattheN-terminustoaHis-tag. |
| BIOLOGicalActivity | ~1.2U/mgprotein.(Substrate:NAD(+ATP)) ~3.8U/mgprotein.(Substrate:NAD(+poly(P)) Oneunitisdefinedastheamountofenzymethatsynthesizes1µmolnicotinamideadeninedinucleotidephosphate(NADP)permin. |
| MW | ~33.0kDa |
| Purity | ≥98%(SDS-PAGE) |
| EndotoxinContent | N/A |
| Concentration | 0.5mg/ml(Lotspecific) |
| Formulation | Liquid.In10mMTRISatpH8.0,containing1mMMgCl2,0.5mMEDTA,1mMDTTand1mMPMSF. |
| OtherProductData | UniProtlinkP0A5S6:NADKinase(M.tuberculosis) |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-80°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
NADkinasecatalyzesthetransferofaphosphategroupfromATPtoNAD+togenerateNADP+,whichinitsreducedformactsasanelectrondonorforbiosyntheticreactions.NADP+isanessentialcoenzymeinmetabolismandprovidesreducingpowertobiosyntheticprocessessuchasfattyacidbiosynthesis.NADkinasefromMycobacteriumtuberculosisisnotATP-dependentbuthasabroadersubstratespecificitythanhumanNADkinase.ItcaneconomicallyproduceNADP+byusingothernucleosidetriphosphatesaswellasinorganicpolyphosphateasasourceofphosphorus.Wasidentifiedasahigh-confidencedrugtarget.
Catalyticactivity:ATP+NAD+=ADP+NADP+
Catalyticactivity:ATP+NAD+=ADP+NADP+
ProductReferences
- CharacterizationofMycobacteriumtuberculosisNADKinase:FunctionalAnalysisoftheFull-LengthEnzymebySite-DirectedMutagenesis:N.Raffaelli,etal.;Biochemistry43,7610(2004)
- ANovelFoldRevealedbyMycobacteriumtuberculosisNADKinase,aKeyAllostericEnzymeinNADPBiosynthesis:S.Garavaglia,etal.;J.Biol.Chem.279,40980(2004)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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