当前位置：
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/LAG-3 (mouse):Fc (mouse) (rec.)/AG-40B-0039-C050/50 µg
Adipogen/LAG-3 (mouse):Fc (mouse) (rec.)/AG-40B-0039-C050/50 µg
商品编号：
AG-40B-0039-C050
品牌：
Adipogen Inc
市场价：
¥6600.00
美元价：
3960.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | LymphocyteActivationGene-3;FDCProtein;CD223 |
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Sequence | Thesequencecodingforthe4extracellularIg-likedomainsofmouseLAG-3(D1-D4)isfusedtotheFcportionofmouseIgG2a(hinge-CH2-CH3). |
| Crossreactivity | Human Mouse |
| Specificity | BindstohumanandmouseMHCclassII. |
| BIOLOGicalActivity | Inducesmaturationofmousedendriticcellsinvitro.InducesCD4andCD8antigen-specificTcellsresponseswhencoinjecteds.c.inmice,togetherwiththeantigen. |
| MW | ~180kDa(SPS-PAGE,nonreducing),~80kDa(SPS-PAGE,reducing) |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.5mg/ml |
| Formulation | Liquid.InPBS. |
| OtherProductData | Application: FlowCytometry:DetectionofMHCclassIImoleculesincombinationwithfluorescentlylabeledantibodiestoIgG2a. Uni-ProtlinkQ61790:LAG-3(mouse) |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Lymphocyteactivationgene3(LAG-3;CD223)playsanimportantroleinnegativelyregulatingTcellproliferation,functionandhomeostasis.ItisrequiredformaximalnaturalandinducedregulatoryTcell(Treg)function.LAG-3iscloselyrelatedtotheTcellco-receptorCD4andbindstoMHCclassIImoleculesbutwithasignificantlyhigheraffinitythanCD4.
ProductReferences
- LAG-3enablesDNAvaccinationtopersistentlypreventmammarycarcinogenesisinHER-2/neutransgenicBALB/cmice:P.Cappello,etal.;CancerRes.63,2518(2003)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
