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Adipogen/Jagged-1 (mouse):Fc (human) (rec.)/AG-40A-0157T-C010/10 µg
Adipogen/Jagged-1 (mouse):Fc (human) (rec.)/AG-40A-0157T-C010/10 µg
商品编号：
AG-40A-0157T-C010
品牌：
Adipogen Inc
市场价：
¥3800.00
美元价：
2280.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Protein Jagged-1; CD339; JAG1 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | Signal peptide and extracellular domain of mouse Jagged-1 (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG. |
| Crossreactivity | Mouse |
| Biological Activity | Inhibits adipogenesis of 3T3L-1 cells. |
| MW | ~150kDa (SDS-PAGE) |
| Purity | ≥90% (SDS-PAGE) |
| Endotoxin Content | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration |
For 10μg size: 0.1 mg /ml after reconstitution. For 50μg size: 1mg/ml after reconstitution. |
| Reconstitution |
For 10μg size: reconstitute with 100μl sterile water. For 50μg size: reconstitute with 50μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | UniProt link Q9QXX0: JAG1 (mouse) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Product References
- Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity: H. Sakai, et al.; PLoS ONE 12, e0177516 (2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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