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Adipogen/Irisin (rec.) (untagged) (E.coli)/AG-40B-0103-5010/5 x 10 µg
Adipogen/Irisin (rec.) (untagged) (E.coli)/AG-40B-0103-5010/5 x 10 µg
商品编号：
AG-40B-0103-5010
品牌：
Adipogen Inc
市场价：
¥6400.00
美元价：
3840.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved) |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Irisin (human, aa 32-143 / mouse, aa 29-140) is untagged. Irisin has 100% identity between mouse, rat, monkey and human. |
| Crossreactivity |
Human Mouse |
| MW | ~12kDa |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
Uni-Prot link Q8NAU1: Irisin |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Product References
- The myokine irisin increases cortical bone mass: G. Colaianni, et al.; PNAS 112, E5763 (2015)
- The myokine irisin is released in response to saturated atty acids and promotes pancreatic beta-cell survival and insulin secretion: A. Natalicchio, et al.; Diabetes 66, 2849 (2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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