脂肪原/IL-6（小鼠）：Fc（人类）（记录）/AG-40B-0108-C010/10µg
商品编号：
AG-40B-0108-C010
品牌：
Adipogen Inc
市场价：
¥1600.00
美元价：
960.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Interleukin-6; B Cell Hybridoma Growth Factor; Interleukin HP-1 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2. |
| Crossreactivity | Mouse |
| Biological Activity | Promotes growth of hybridoma/plasma cells at concentration <0.1ng l.=""> |
| MW | 50kDa |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.01eu mu;g="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.1 mg /ml after reconstitution |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
Uniprot link P08505 : IL-6 (mouse)
AfCS Signalling Gateway link A004204: IL-6 (mouse) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Interleukin 6 (IL-6) is a pleiotropic α-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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