Adipogen/IL-6 (human) (rec.)/YIF-LF-P0221/20 µg
商品编号：
YIF-LF-P0221
品牌：
Adipogen Inc
市场价：
¥6080.00
美元价：
3648.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CDF;IL6;IL-6;BSF-2;IFNB2;IFN-β-2;Interleukin-6;Interferonβ-2;HybridomaGrowthFactor;CTLDifferentiationFactor;B-CellStimulatoryFactor2 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Crossreactivity | Human |
| BIOLOGicalActivity | TheED50ofIL-6istypically0.3-1ng/ml.Measuredinacellproliferationassayusingamurinemyeloblasticcellline,B9. |
| Purity | ≥95%(SDS-PAGE) |
| Concentration | 1mg/ml |
| Formulation | LiquidinPBS,10%glycerol. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Interleukin-6(IL-6)isapleiotropicα-helicalcytokinethatplaysimportantrolesinacentralplayerintheregulationofinflammation,haematopoiesis,immuneresponseandhostdefensemechanisms.HumanIL-6molecularweightrangesbetween21and28kDa,dependingonthestateofglycosylationandphosphorylation.MaturehumanIL-6is183aminoacidsandsharesthehomologybetweenhumanandratIL-6is41%attheaminoacidlevel.IL-6interactswithitsreceptorcomplexconsistingofthemembrane-boundIL-6receptor(IL-6R)andthesignaltransducingproteingp130.IL-6Rcanexistasasolubleprotein(sIL-6R),whichbindstheligandIL-6.Thissolublecomplexcanbindtogp130oncellsthatlackthemembrane-boundIL-6Randinitiatesignaling.TwomajorsignallingpathwaysareactivatedbyIL-6:theJAK/STATpathwayandMAPKcascade.
ProductReferences
1)HoeneMandWeigertC.,(2008)ObesRev(1):20-9.(General)
2)HondDSetal.,(2007)Cancer110(9):1911-28.(General)
3)KnupferHandPreissR.,(2008)ImmunologyandCellBiology86,87-91.(General)
2)HondDSetal.,(2007)Cancer110(9):1911-28.(General)
3)KnupferHandPreissR.,(2008)ImmunologyandCellBiology86,87-91.(General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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