当前位置:
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/IL-38 (human) (rec.) (His)/AG-40A-0191-C010/10 µg

Adipogen/IL-38 (human) (rec.) (His)/AG-40A-0191-C010/10 µg
商品编号:
AG-40A-0191-C010
品牌:
Adipogen Inc
市场价:
¥4400.00
美元价:
2640.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Interleukin-38;Interleukin-1FamilyMember10theta;IL-1F10;FIL1theta;FKSG75;IL-1HY2;IL1-theta;Interleukin-1HY2;Interleukin-1ReceptorAntagoNISTFKSG75 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | HumanIL-38(aa1-152)isfusedattheC-terminustoaHis-tag. |
Crossreactivity | Human |
MW | ~18kDa(SDS-PAGE) |
Purity | ≥95%(SDS-PAGE) |
PurityDetail | PurifiedusingNi-NTAcolumnandFPLC. |
EndotoxinContent | <1eu g="" purified="" protein="" (lal="" test;="" lonza).="">1eu> |
Reconstitution | Reconstituteindistilledwater. |
Formulation | Lyophilizedfrom0.2μm-filteredsolutionin55mMTRIS-Cl,pH8.2,containing150mMNaCl. |
OtherProductData | UniProtlinkQ8WWZ1:IL-38(human) |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Avoidfreeze/thawcycles. |
Use/StABIlity | Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
Documents | |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
IL-38(IL-1F10)mRNAisexpressedinheart,placenta,fetalliver,spleen,thymusandtonsil.TheexpressioninavarietyofimmunetissuesandsimilaritytoIL-1RasuggestaroleofIL-1F10intheinflammatoryresponse.IthasbeenreportedthatremovaloftheN-terminusdomainoftheinterleukinsoftheIL-1FfamilysuchasIL-1F5/6/8or9(alsocalledIL-36Ra,IL-36α,IL-36βorIL-36γ)isimportanttoincreasetheirBIOLOGicalactivity.RecentlyithasbeenshownthatIL-38isN-terminallyprocessedandsecretedbyapoptoticcells.ReleasedprocessedIL-38(20-152)bindstothereceptorInterleukin-1receptoraccessoryprotein-like1(IL1RAPL1;TIGIRR-2)atthesurfaceofmacrophages.ProcessedIL-38-activatedIL1RAPL1reducestheproductionofIL-6leADIngtoinflammationattenuation.
ProductReferences
- Interleukin-38isreleasedfromapoptoticcellstolimitinflammatorymacrophageresponses:J.Mora,etal.;J.Mol.CellBiol.(Epubaheadofprint)(2016)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
联络我们