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Adipogen/IL-37 (human) (rec.) (His)/AG-40A-0174Y-C010/10 µg
Adipogen/IL-37 (human) (rec.) (His)/AG-40A-0174Y-C010/10 µg
商品编号：
AG-40A-0174Y-C010
品牌：
Adipogen Inc
市场价：
¥4000.00
美元价：
2400.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Interleukin-1FamilyMember7;IL-1F7;FIL1zeta;IL-1X;Interleukin-1Homolog4;IL-1H4;Interleukin-1zeta;IL-1zeta;IL-1RP1;IL1F7;FIL1Z,IL1H4,IL1RP1 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | HumanIL-37(aa1-218)isfusedattheC-terminustoaHis-tag. |
| Crossreactivity | Human |
| MW | ~30kDa(SDS-PAGE) |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.01eu g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.1mg/mlafterreconstitution. |
| Reconstitution | Reconstitutewith100μlsterilewater. |
| Formulation | Lyophilized.ContainsPBS. |
| OtherProductData | UniProtlinkQ9NZH6:IL-37(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
IL-37(IL-1F7;IL-1H4)isanIL-1familymemberthatisexpressedonlyincertaintypesofhumanorgansandcellssuchasheart,thymus,testis,kidney,mononuclearcells(PBMCs)anddendriticcells.IL-37isaninhibitorofinnateimmunitywithanti-inflammatoryproperties.Itbindstotheinterleukin-18receptor(IL-18R)anditsco-receptorSIGIRR.IL-37issecretedasafull-lengthandasaprocessedformstartingfromaminoacidVal46.Itplaysanimportantroleasalinkbetweeninnateandadaptiveimmunityandactsasaninhibitorofautoimmunediseasesandtumorgrowth.IL-37alsoinhibitedLipopolysaccharide(LPS)-inducedimmunologicalreactionandLPS-inducedosteoclastformationandboneresorption.
ProductReferences
- Interleukin-37amelioratesmyocardialischemia/reperfusioninjuryinmice:B.Wu,etal.;Clin.Exp.Immunol.176,438(2014)
- TheevaluationofplasmaandleukocyticIL-37expressioninearlyinflammationinpatientswithacuteST-segmentelevationmyocardialinfarctionafterPCI:X.Wang,etal.;Med.Inflamm.2015,ID626934(2015)
- TheprotectiveeffectofInterleukin-37onvascularcalcificationandatherosclerosisinapolipoprotein:M.Chai,etal.;J.InterferonCytok.Res.35,530(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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