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脂肪原/IL-36Ra(aa 2-155)(人类)(rec.)(未标记)/AG-40B-0097-3010/3 x 10µg

脂肪原/IL-36Ra(aa 2-155)(人类)(rec.)(未标记)/AG-40B-0097-3010/3 x 10µg
商品编号:
AG-40B-0097-3010
品牌:
Adipogen Inc
市场价:
¥6400.00
美元价:
3840.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Interleukin-36ReceptorAntagoNISTProtein;IL-1F5;Interleukin-1FamilyMember5;IL-1δ;Interleukin-1δInterleukin-1Homolog3;Interleukin-1-likeProtein1 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | HumanIL36Ra(aaVal2-Asp155)isuntagged. |
Crossreactivity | Human |
Application | InhibitionofBIOLOGicalactivityofIL-36α(IL-1F6),IL-36β(IL-1F8),andIL-36γ(IL-1F9). |
MW | ~17kDa |
Purity | ≥95%(SDS-PAGE) |
EndotoxinContent | <0.05eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.05eu> |
Concentration | 0.1mg/mlafterreconstitution. |
Reconstitution | Reconstitutewith100μlsterilewater. |
Formulation | Lyophilized.ContainsPBS. |
OtherProductData | Uni-ProtlinkQ9UBH0:Interleukin-36receptorantagonistprotein |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
IL-36Ra/IL-1F5isahighlyandaspecificantagonistoftheIL-1receptor-relatedprotein2-mediatedresponsetoIL-36α(IL-1F6),IL-36β(IL-1F8)andIL-36γ(IL-1F9).ThesecytokinesbindtoIL-36R(IL-1Rrp2)andIL-1RAcP,activatingsimilarintracellularsignalsasIL-1.IL-36Rainhibitstheproductionofproinflammatorycytokines,includingIL-12,IL-1β,IL-6,TNF-αandIL-23inducedbyIL-36inBMDCandCD4Tcells.SkinanddendriticcellsaretargetoftheIL-36interleukinsleADIngtoaTh1response.RecentlymutationsthataffectthelevelsandtheactivityofIL-36Rahavebeenfoundinpatientswithpustularpsoriasis,leadingtoenhancedproductionofinflammatorycytokines(IL-8inparticular)bykeratinocytes.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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