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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/IL-37 (aa 46-218) (human) (rec.) (His)/AG-40A-0190-C010/10 µg
商品详细Adipogen/IL-37 (aa 46-218) (human) (rec.) (His)/AG-40A-0190-C010/10 µg
Adipogen/IL-37 (aa 46-218) (human) (rec.) (His)/AG-40A-0190-C010/10 µg
Adipogen/IL-37 (aa 46-218) (human) (rec.) (His)/AG-40A-0190-C010/10 µg
商品编号: AG-40A-0190-C010
品牌: Adipogen Inc
市场价: ¥6000.00
美元价: 3600.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsInterleukin-1FamilyMember7;IL-1F7;FIL1zeta;IL-1X;Interleukin-1Homolog4;IL-1H4;Interleukin-1zeta;IL-1zeta;IL-1RP1;IL1F7;FIL1Z,IL1H4,IL1RP1
ProductTypeProtein
Properties
Source/HostE.coli
SequenceHumanIL-37(aaVal46-Asp218)isfusedattheC-terminustoaHis-tag.
CrossreactivityHuman
MW~20kDa(SDS-PAGE)
Purity≥95%(SDS-PAGE)
PurityDetailPurifiedusingNi-NTAcolumnandFPLC.
EndotoxinContent<0.1eu g="" purified="" protein="" (lal="" test;="" lonza).="">
ReconstitutionReconstituteindistilledwater.
FormulationLyophilizedfrom0.2μm-filteredsolutionin55mMTRIS-Cl,pH8.2,containing150mMNaCl.
OtherProductDataUniProtlinkQ9NZH6:IL-37(human)
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAfterreconstitution,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
Use/StABIlityStableforatleast6monthsafterreceiptwhenstoredat-20°C.
Workingaliquotsarestableforupto3monthswhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF

IL-37(IL-1F7;IL-1H4)isanIL-1familymemberthatisexpressedonlyincertaintypesofhumanorgansandcellssuchasheart,thymus,testis,kidney,mononuclearcells(PBMCs)anddendriticcells.IL-37isaninhibitorofinnateimmunitywithanti-inflammatoryproperties.Itbindstotheinterleukin-18receptor(IL-18R)anditsco-receptorSIGIRR.IL-37issecretedasafull-lengthandasaprocessedformstartingfromaminoacidVal46.Itplaysanimportantroleasalinkbetweeninnateandadaptiveimmunityandactsasaninhibitorofautoimmunediseasesandtumorgrowth.IL-37alsoinhibitedLipopolysaccharide(LPS)-inducedimmunologicalreactionandLPS-inducedosteoclastformationandboneresorption.

品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。