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Adipogen/IL-22 (human):Fc (human) (rec.) (non-lytic)/CHI-HF-22022-C025/25 µg

Adipogen/IL-22 (human):Fc (human) (rec.) (non-lytic)/CHI-HF-22022-C025/25 µg
商品编号:
CHI-HF-22022-C025
品牌:
Adipogen Inc
市场价:
¥4600.00
美元价:
2760.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | Interleukin-22;IL-10-relatedTCell-derived-inducIBLeFactor |
ProductType | Protein |
Properties | |
Source/Host | CHOcells |
Sequence | TheextracellulardomainofhumanIL-22(aa34-179)isfusedtotheN-terminusoftheFcregionofamutanthumanIgG1. |
Crossreactivity | Human |
BIOLOGicalActivity | ShowsthebiologicalfunctionoftheIL-22moietyandexertsaprolongedcirculatinghalf-lifecausedbythemodifiedFcdomain. |
Purity | ≥98%(SDS-PAGE) |
EndotoxinContent | <0.06eu mu;g="" protein="" (lal="" test;="" lonza).="">0.06eu> |
Reconstitution | Reconstitute25µgvialin250µlsterilewater. Reconstitute50µgvialin50µlsterilewater. Add1XPBStothedesiredproteinconcentration. |
Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
OtherProductData | Non-lytic:Actsasalonglastingfusionproteinwhichonlybindstothereceptor.Mutationstothecomplement(C1q)andFcgRIbindingsitesoftheIgGsFcfragmentrenderthefusionproteinsincapableofantibodydirectedcytotoxicity(ADCC)andcomplementdirectedcytotoxicity(CDC). NCBIreferenceNP_065386.1:IL-22(human) |
Declaration | ManufacturedbyChimerigen. |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Avoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
Interleukin-22(IL-22),alsoknownasIL-10relatedTcellderivedinduciblefactor(ILTIF)wasinitiallyidentifiedasageneinducedbyIL-9inmouseTcellsandmastcells.IL-22hasbeenshowntoactivateSTAT1andSTAT3inseveralhepatomacelllinesandupregulatetheproductionofacutephaseproteins.IL-22isproducedbynormalTcellsuponanti-CD3stimulationinhumans.MouseIL-22expressionisalsoinducedinvariousorgansuponlipopolysaccharideinjection,suggestingthatIL-22maybeinvolvedininflammatoryresponses.ThefunctionalIL-22receptorcomplexconsistsoftworeceptorsubunits,IL-22R(CRF29)andIL-10Rβ(CRF24),belongingtotheclassIIcytokinereceptorfamily.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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