当前位置：
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/IL-2 (C145S Mutant) (human) (rec.) (His)/CHI-HF-20102-C010/10 µg
Adipogen/IL-2 (C145S Mutant) (human) (rec.) (His)/CHI-HF-20102-C010/10 µg
商品编号：
CHI-HF-20102-C010
品牌：
Adipogen Inc
市场价：
¥3000.00
美元价：
1800.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Interleukin-2;Aldesleukin |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | HumanIL-2(aa21-153)(mutationC145S)isfusedattheC-terminustoaHis-tag. |
| Crossreactivity | Human Mouse |
| BIOLOGicalActivity | MeasuredbyitsABIlitytostimulatetheproliferationofmouseCTLL-2cells.TheED50forthiseffectistypically0.1ng/mL,correspondingtoaspecificactivityof1x107units/mg. |
| MW | ~19kDa(SDS-PAGE) |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.01eu mu;g="" protein="" (lal="" test;="" lonza).=""> |
| Reconstitution | Reconstitute10µgvialwith100µlsterilewatertoaconcentrationof0.1mg/ml. Reconstitute50µgvialwith100µlsterilewatertoaconcentrationof0.5mg/ml. Add1XPBStothedesiredproteinconcentration. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceNP_000577.2:IL-2(human) |
| Declaration | ManufacturedbyChimerigen. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/Stability | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Interleukin-2(IL-2)isa133aminoacidglycoproteinwithoneintramoleculardisulfidebondandvariableglycosylation.ItissecretedbyactivatedTcellsandinducesproliferationandmaturationofactivatedTcells,naturalkillercells,andlymphokineactivatedkillercells.IL-2alsostimulatesproliferationofantibody-producingBcells,activatesneutrophils,andinducesmononuclearcellstosecreteIFN-γandTNF-αand-β.Moreover,studieshaveshownthatIL-2isrequiredforactivation-inducedapoptosis,animportanthemeostaticmechanismintheimmunesystem,whichisinvolvedinthemaintenanceofperipheraltolerancetoself-antigens.ThemodifiedIL-2proteincontainingasubstitutionatpositionC145Sretainsfullbiologicalactivity,suggestingthatthecysteineatthispositionisnotinvolvedinadisulfidebondandthatafreesulfhydrylgroupatthatpositionisnotnecessaryforreceptorbinding.Additionally,theC145Smutationinsertionavoidsnon-specificdisulfidesandimprovesthephysicalpropertiesoftheprotein.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
