Adipogen/HSP90α (human) (rec.)/AG-40T-0273-C050/50 µg
商品编号：
AG-40T-0273-C050
品牌：
Adipogen Inc
市场价：
¥8420.00
美元价：
5052.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | HeatShockProtein90α;HSP86;HSP90A;HSP90AA1;HSP90N;HSPC1;HSPCA;HSPN;LAP2;Lipopolysaccharide-associatedProtein2;RenalCarcinomaAntigenNY-REN-38 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | HumanHSP90α(AccessionNr.P07900). |
| Crossreactivity | Human |
| Formulation | Liquid.In50mMHepespH7.5,50mMKCl,1mMTCEP. |
| OtherProductData | Use:Thisproteinworksinconjunctionwiththeco-chaperonep23/PTGES3.Bothproteinsarerequiredforenzymaticactivityinvariousinvitroproteinrefoldingassays.Typicalenzymeconcentrationforuseinvitroisdependentonspecificapplication.Werecommendaninitialp23/PTGES3concentrationof2-3μM,andHSP90α/HSP90AA1concentrationequimolar(orabove)top23/PTGES3. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
MembersoftheHSP90familyareessentialchaperonesfoundinallorganismsfrombacteriatohumans.HSP90complexesofteninteractwithproteinsintheirnativeconformationandhelptomaintain/stabilizeligand-boundstates.Inthiscapacity,HSP90playsacentralroleinfunctionandturnoverofmanyproteinsinvolvedinprocessessuchassignaltransduction,cellcyclecontrolandCancer.HSP70familymembersandHSP90complexesfrequentlyactintandem,withtheformerparticipatinginthefoldingoftheclientproteinsandHSP90stabilizingtheminawayfavorableforinteractionwithligands.HSP90formscomplexeswithanarrayofco-chaperonesthatbothregulateitsinteractionwithclientproteinsandstimulateitsATPaseactivity.Bybindingtodifferentco-chaperonesHSP90acquiresspecificityfordifferentfamiliesofclientproteins.ManyoftheHSP90-clientproteinsareinvolvedintumorcellgrowthandHSP90inhibitorsareimportantaspotentialanticancerdrugs.InhibitionofHSP90alsopreventstheformationofproteinaggregatesinmodelsofParkinsondisease,Huntingtondisease,andothers.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
