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Adipogen/HpARI (Alarmin Release Inhibitor) (rec.) (His)/AG-40B-0178-3050/3 x 50 µg

Adipogen/HpARI (Alarmin Release Inhibitor) (rec.) (His)/AG-40B-0178-3050/3 x 50 µg
商品编号:
AG-40B-0178-3050
品牌:
Adipogen Inc
市场价:
¥12000.00
美元价:
7200.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | HeligmosomoidesPolygyrusAlarminReleaseInhibitor |
ProductType | Protein |
Properties | |
Source/Host | HEK293cells |
Sequence | HeligmosomoidespolygyrusproteinHpARI(aa17-251)isfusedattheC-terminustoaHis-tag. |
Crossreactivity | Human Mouse |
Specificity | BindstohumanandmouseIL-33. |
MW | ~40kDa |
Purity | ≥90%(SDS-PAGE) |
EndotoxinContent | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu> |
Concentration | Afterreconstitution:1mg/ml |
Reconstitution | Reconstitutewith50μlsterilewater. |
Formulation | Lyophilized.ContainsPBS. |
OtherProductData | WormbaseHPBE_0000813301:HeligmosomoidespolygyrusproteinHpARI |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
HpARIisaproteinsecretedbythemouseparasiteHeligmosomoidespolygyrus.ThematureproteinHpARI,containingthreepredictedComplementControlProtein(CCP)-likemodules(alsoknownasShortConsensusRepeats(SCRs)orsushi-domains),suppressestype2(allergic)immuneresponsesthroughinterferenceintheinterleukin-33(IL-33)pathway.Duringcelldamage,HpARIgainsaccesstothenucleusofnecroticcells,whereitbindsdirectlytoIL-33andnuclearDNA,preventingsecretionandbindingofIL-33toitsreceptor.HpARIisanewtypeofreagenttopreventIL-33-mediatedpathology.
ProductReferences
- HpARIproteinsecretedbyahelminthparasitesuppressesinterleukin-33:M.Osbourne,etal.;Immunity47,739(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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