脂肪原/HGF（人类）（记录）/AG-40T-0042-C005/5µg
商品编号：
AG-40T-0042-C005
品牌：
Adipogen Inc
市场价：
¥3000.00
美元价：
1800.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | HepatocyteGrowthFactor;Hepatopoietin-A;ScatterFactor |
| ProductType | Protein |
| Properties | |
| Source/Host | Sf9cells |
| Sequence | HumanHGF(692aa). |
| Crossreactivity | Human |
| BIOLOGicalActivity | TheactivitywasassayedforscatteringactivityintheMDCKcellassay.TheED50forthiseffectistypicallyat1.0-5.0ng/ml. |
| MW | ~78kDa |
| Purity | ≥90%(SDS-PAGE) |
| Reconstitution | HGFissolubleinaceticacid(50mM),waterandmostaqueousbuffersandcanbereconstitutedtoaconcentrationof100µg/ml.Furtherdilutionsshouldbemadeintobuffercontainingproteinormediumcontainingserum. |
| Formulation | Lyophilized. |
| OtherProductData | UniProtlinkP14210:HGF(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Humanhepatocytegrowthfactor(HGF)issynthesizedasabiologicallyinactivesinglechainprecursor,whichiscleavedbyaspecific,extracellularserumserineproteasetoafullyactiveheterodimer.Itstimulatesthemotilityandinvasionofseveralcancercelltypesandcaninduceangiogenesis.AllbiologicalresponsesinducedbyHGFareelicitedbybindingtoitstransmembranetyrosinekinasereceptor.HGFfunctionisessentialfornormaldevelopment.Knockoutstudieshavedemonstratedthatbothligandandreceptordeficientmicedisplayanembryoniclethalphenotype.HGFsynergizeswithbasicFGFintheinductionofangiogenesis.HGFisapotentmitogenformatureparenchymalhepatocytecellsandisapleiotrophiccytokine.Itactsasgrowthfactorforabroadspectrumoftissuesandcelltypes.Ithasnodetectableproteaseactivity.ItisanactivatingligandforthereceptortyrosinekinaseMETbybindingandpromotingitsdimerization.
ProductReferences
FunctionalanalysisofHGF/METsignalingandaberrantHGF-activatorexpressionindiffuselargeB-celllymphoma:EP.Tjin,etal.;Blood107,760(2006)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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