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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/GCN5 (human) (rec.) (His) (highly active)/AG-40T-0017-C002/2 µg
商品详细Adipogen/GCN5 (human) (rec.) (His) (highly active)/AG-40T-0017-C002/2 µg
Adipogen/GCN5 (human) (rec.) (His) (highly active)/AG-40T-0017-C002/2 µg
Adipogen/GCN5 (human) (rec.) (His) (highly active)/AG-40T-0017-C002/2 µg
商品编号: AG-40T-0017-C002
品牌: Adipogen Inc
市场价: ¥4000.00
美元价: 2400.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsGCN5L2;HistoneAcetyltransferaseGCN5;HistoneAcetyltransferaseKAT2A;LysineAcetyltransferase2A;STAF97
ProductTypeProtein
Properties
Source/HostSf21cells
SequenceHumanGCN5isfusedtoaHis-tag.
CrossreactivityHuman
BIOLOGicalActivity~200-300ngarerequiredforstandardHATassay.
Purity≥95%(SDS-PAGE)
ConcentrationLotdependent(0.2-0.5mg/ml)
FormulationLiquid.In50mMTRIS-HCl,pH7.5,containing100mMsodiumchloride,0.2%NP-40,50mMimidazoleand10%glycerol.
OtherProductDataUniProtIDQ92830:GCN5(human)
ShippingandHandling
ShippingDRYICE
ShortTermStorage-20°C
LongTermStorage-80°C
HandlingAdviceAfteropening,preparealiquotsandstoreat-80°C.
Avoidfreeze/thawcycles.
Use/StABIlityStableforatleast6monthsafterreceiptwhenstoredat-80°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
GCN5functionsasahistoneacetyltransferase(HAT)topromotetranscriptionalactivation.Acetylationofhistonesgivesaspecifictagforepigenetictranscriptionactivation.Ithassignificanthistoneacetyltransferaseactivitywithcorehistones,butnotwithnucleosomecoreparticles.IncaseofHIV-1infection,itisrecruitedbytheviralproteinTat.ItregulatesTat"stransactivatingactivityandmayhelpinducingchromatinremodelingofproviralgenes.GCN5isacomponentoftheAdaTwo-Acontaining(ATAC)complex,acomplexwithhistoneacetyltransferaseactivityonhistonesH3andH4.
ProductReferences
  1. Functionalrelevanceofnovelp300-mediatedlysine314and315acetylationofRelA/p65:C.Buerki,etal.;NucleicAcidsRes.36,1665(2008)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。