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Adipogen/GABARAP [ATG8A] (human) (rec.) (His) (Biotin)/AG-40T-0260B-C050/50 µg
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Adipogen/GABARAP [ATG8A] (human) (rec.) (His) (Biotin)/AG-40T-0260B-C050/50 µg
商品编号：
AG-40T-0260B-C050
品牌：
Adipogen Inc
市场价：
¥3080.00
美元价：
1848.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | γ-AminobutyricAcidTypeAReceptorAssociatedProtein;GABA(A)Receptor-associatedProtein;Apg8p1;ATG8A;FLC3B;MM46 |
| ProductType | Protein |
| Properties | |
| Source/Host | E.coli |
| Sequence | HumanGABARAP(AccessionNr.NP_009209)fusedtoaN-terminalHis-tagandconjugatedtobiotin. |
| Crossreactivity | Human |
| Label/Conjugates | Biotin |
| Formulation | Liquid.In50mMHepespH7.5,150mMNaCl,2mMDTT. |
| OtherProductData | Use:ModifiedwithbiotinviaprimaryaminecouplingresultinginmodificationoflysineresiduesaswellastheN-terminus.Canbedetectedusingavidin-linkedreagentsforhigherefficiencyanddetectionsensitivitythanwithantibodies.Dependingonexperimentalconditionsanddetectionmethod,suggestedinvitroconcentrationsforthiolesterformationis1-5μM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
γ-AminobutyricAcidReceptor-associatedProtein(GABARAP),alsoknownasApg8p1,is117aminoacid(aa)proteinwithapredictedmolecularweightof14kDa.ItisamemberoftheGABARAPsubfamilyoftheautophagy-related8(Atg8)familyofproteins.TheGABARAPsubfamilyalsoincludesGABARAPL1.GABARAPhas100%aasequenceidentitywithitsmouseandratorthologsandisorthologoustoyeastAtg8.Atg8familymembersshowstructuralsimilaritywithubiquitin,butlackaasequencesimilarity.GABARAPwasfirstdescribedforitsputativeinvolvementGABAAReceptortrafficking.However,itisbestknownforitsroleinautophagy.GABARAPcovalentlyattachestophosphatidylethanolamine(PE)inthephagophore(autophagosomeprecursor)membraneusingaubiquitin-likeconjugationsystemthatincludesubiquitin-activating(E1)-,ubiquitin-conjugating(E2)-,andubiquitinligase(E3)-likeenzymes.Hereitisinvolvedinthelaterstagesofautophagosomematuration.Itmayalsobeinvolvedincargorecruitmenttoautophagosomes.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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