脂肪原/Fn14（人类）：Fc（人类）（rec.）/AG-40B-0034-3050/3 x 50µg
商品编号：
AG-40B-0034-3050
品牌：
Adipogen Inc
市场价：
¥10000.00
美元价：
6000.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | TumorNecrosisFactorReceptorSuperfamilyMember12A;FGF-inducIBLe14;Tweak-receptor;CD266;TNFRSF12A |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | TheextracellularregionofhumanFN14(aa28-75)isfusedattheC-terminustotheFcportionofhumanIgG1. |
| Crossreactivity | Human Mouse |
| Specificity | BindstomouseandhumanTWEAK. |
| MW | ~35kDa(SDS-PAGE). |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 1mg/mlafterreconstitution. |
| Reconstitution | Reconstitutewith50μlsterilewater. |
| Formulation | Lyophilized.ContainsPBS. |
| OtherProductData | UniProtlinkQ9NP84:FN14(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afterreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
TWEAKisacytokinethatcontrolsproliferation,migration,differentiation,apoptosis,angiogenesisandinflammation.TWEAKbindstoFn14,ahighlyinduciblecell-surfacereceptorthatislinkedtoseveralintracellularsignallingpathways,includingthenuclearfactor-B(NF-κB)pathway.TheTWEAK–Fn14axisplaysabeneficialroleintissuerepairfollowingacuteinjuryandmaycontributetocancer,chronicautoimmunediseasesandacuteischaemicstroke.
ProductReferences
- NoevidencethatsolubleTACIinducessignallingviamembrane-expressedBAFFandAPRILinmyeloidcells:J.Nys,etal.;PLoSOne8,e61350(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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