脂肪原/FLT3配体(人)(受体)(His)/CHI-HF-201FLT3L-C010/10µg
商品编号:
CHI-HF-201FLT3L-C010
品牌:
Adipogen Inc
市场价:
¥3600.00
美元价:
2160.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | FLT3L;FMS-likeTyrosineKinase3Ligand |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | HumanFLT3L(aa27-184)isfusedattheC-terminustoaHis-tag. |
| Crossreactivity | Human Mouse |
| BIOLOGicalActivity | TheED50wasdeterminedbythedose-dependentstimulationoftheproliferationofhumanAML5cellsis≤1.0ng/ml,correspondingtoaspecificactivityof≥1x106units/mg. |
| MW | ~25kDa(SDS-PAGE) |
| Purity | ≥95%(SDS-PAGE) |
| EndotoxinContent | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.01eu> |
| Reconstitution | Reconstitute10µgvialwith100µlsterilewatertoaconcentrationof0.1mg/ml. Reconstitute50µgvialwith100µlsterilewatertoaconcentrationof0.5mg/ml. Add1XPBStothedesiredproteinconcentration. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceAAI26294.1:FLT3L(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
FMS-liketyrosinekinase3ligand(FLT3L)actsasagrowthfactorthatincreasesthenumberofimmunecells(lymphocytes(BcellsandTcells))byactivatingthehematopoieticProgenitors.ItbindstoFLT3(CD135)whichisfoundonmultipotentprogenitor(MPP)andcommonlymphoidprogenitor(CLP)cellsinmice.FLT3Linducesthemobilizationofthehematopoieticprogenitorsandstemcellsinvivowhichmayhelpthesystemtokillcancercells.FLT3Liscrucialforsteady-statepDC(plasmacytoiddendriticcells)andcDC(classicaldendriticcells)development.DeficiencyofFLT3LcausesadramaticdecreaseinDCnumbers,whereasincreasingitsavailabilityincreaseinDCnumbers.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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