当前位置：
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/FGF-23 (human) (rec.) (His)/AG-40A-0114Y-C010/10 µg
Adipogen/FGF-23 (human) (rec.) (His)/AG-40A-0114Y-C010/10 µg
商品编号：
AG-40A-0114Y-C010
品牌：
Adipogen Inc
市场价：
¥3800.00
美元价：
2280.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | FibroblastGrowthFactor23;Tumor-derivedHypophosphatemia-inducingFactor |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | SignalpeptideandhumanFGF-23(aa1-251)arefusedattheC-terminustoaHis-tag. |
| Crossreactivity | Human |
| BIOLOGicalActivity | ActivatesERKandFRS2αphosphorylationinKlothoexpressingcells. |
| MW | ~30kDa(SDS-PAGE,full-length).FGF23iscleavedbetweenArg179andSer180(twobandsof~14kDaand~16kDa). |
| Purity | ≥90%(SDS-PAGE) |
| EndotoxinContent | <0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 0.1mg/mlafterreconstitution. |
| Reconstitution | Reconstitutewith100μlsterilewater. |
| Formulation | Lyophilized.ContainsPBS. |
| OtherProductData | UniProtlinkQ9GZV9:FGF-23(human) |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast6monthsafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
FGF-23(Fibroblastgrowthfactor23)isaregulatorofphosphatehomeostasis.ItupregulatesEGR1expressioninthepresenceofKLBy.ActsdirectlyontheparathyroidtodecreasePTHsecretion.Regulatesthevitamin-Dmetabolism.Negativelyregulatesosteoblastdifferentiationandmatrixmineralization.DefectsinFGF-23arethecauseofautosomaldominanthypophosphataemicrickets(ADHR)andofhyperphosphatemicfamilialtumoralcalcinosis(HFTC).
ProductReferences
- Maternally-derivedantibodytofibroblastgrowthfactor-23reduceddietaryphosphaterequirementsingrowingchicks:E.A.Bobeck,etal.;BBRC420,666(2012)
- Antibodytofibroblastgrowthfactor23-peptidereducesexcretaphosphorusoflayinghens:Z.Ren,etal.;PoultryScience96,127(2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
