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Adipogen/FAT10 (human) (rec.) (Agarose)/AG-40T-0256-R500/500 µl

Adipogen/FAT10 (human) (rec.) (Agarose)/AG-40T-0256-R500/500 µl
商品编号:
AG-40T-0256-R500
品牌:
Adipogen Inc
市场价:
¥5160.00
美元价:
3096.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | UbiquitinD;UBD;Ubiquitin-likeProteinFAT10 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | HumanFAT10(AccessionNr.O15205)coupledtoagarose. |
Crossreactivity | Human |
Label/Conjugates | Agarose |
Formulation | Liquid.In50mMHEPESpH7.5,250mMNaCl,0.09%SodiumAzide. |
OtherProductData | Use:CovalentlycoupledtoagarosebeadsviaprimaryaminesallowingforafullyfunctionalC-terminus.IdealfortheenrichmentofknownFAT10-interactingproteinsaswellasthediscoveryofnovelFAT10-interactingproteins.Werecommendequilibratingtheresinbywashingwith5-10mlofyourdesiredaqueousbuffer. |
Declaration | ManufacturedbyBostonBiochem |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Donotfreeze. |
Use/StABIlity | Stableforatleast3monthsafterreceiptwhenstoredat+4°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
LeukocyteAntigen-FAssociatedTranscript10(FAT10),alsoknownasubiquitinD(UBD),isa165aminoacid(aa)memberoftheubiquitin-likefamilyofproteins.HumanFAT10hasapredictedmolecularweightof18.5kDaandshares69%aasequenceidentitywithmouseFAT10.HumanFAT10mRNAisexpressedasasingletranscriptinlymphoblastoidlinesanddendriticcells,butmorethanonemRNAtranscripthasbeenidentifiedformurineFAT10.FAT10canbeinducedbyIFN-γandTNF-αinsomecelllines.Structurally,FAT10consistsoftwoubiquitin-likedomainsthatareconnectedbyashortlinker.Likeubiquitin,FAT10hasaC-terminalglycineresiduethatcanbeusedtoformisopeptidebondswithtargetproteins.FAT10-conjugatedproteinsaretargetedtotheproteasomewherethe26SProteasomesubunitangiocidinbindstoFAT10andenablessubsequentdegradationoftheconjugatedprotein.Inadditiontoangiocidin,FAT10hasbeenshowntointeractwithHuntingtin,Ataxin-1,MAD2andNUB1L.FAT10hasbeenimplicatedinanumberofBIOLOGicalprocessessuchascellcyclecontrol,antigenpresentationandcytokineresponse.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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