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Adipogen/E6 (Human Papillomavirus Type 16) (rec.)/AG-40T-0254-C025/25 µg

Adipogen/E6 (Human Papillomavirus Type 16) (rec.)/AG-40T-0254-C025/25 µg
商品编号:
AG-40T-0254-C025
品牌:
Adipogen Inc
市场价:
¥4060.00
美元价:
2436.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | EarlyProtein6;HpV16gp1 |
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | HPVType16E6(AccessionNr.Q547J2),containssixcysteine-to-serinesubstitutionsatpositions23,58,87,104,118,and147(HPVtype16sequencenumbering). |
Crossreactivity | Virus |
Formulation | Liquid.In50mMHepespH7.0,400mMNaCl,2mMDTT. |
OtherProductData | Use:TypicalconcentrationtosupportE6AP-mediatedp53ubiquitinationinvitrois0.1-2μM,dependingonexperimentalconditions. |
Declaration | ManufacturedbyBostonBiochem |
ShippingandHandling | |
Shipping | DRYICE |
ShortTermStorage | -20°C |
LongTermStorage | -80°C |
HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
E6(Earlyprotein6)isaviralproteinproducedincellsinfectedwiththeHumanPapillomavirus.E6formsacomplexwiththehostcellubiquitinligaseE6AP(E6-Associated-Protein)generatingaligaseactivitythatpolyubiquitinatestumorsuppressorsp53andp73andtargetsthemtothe26Sproteasomefordegradation.AsaresultDNAdamageandchromosomalinstabilitiesincrease,oftenleADIngtocellproliferationandcancer.TheE6/E6APcomplexalsotargetsothersubstratesforubiquitination,suchasTERT,BAK1,FADD,andpro-CASP8—noneofwhichappeartobesubstratesforE6APintheabsenceofE6.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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