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Adipogen/Diazepam Binding Inhibitor (human) (rec.)/YIF-LF-P0046/0.5 mg
Adipogen/Diazepam Binding Inhibitor (human) (rec.)/YIF-LF-P0046/0.5 mg
商品编号：
YIF-LF-P0046
品牌：
Adipogen Inc
市场价：
¥4200.00
美元价：
2520.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | EP; DBI; ACBP; Endozepine; Acyl-CoA-binding Protein; Diazepam-binding Inhibitor |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Crossreactivity | Human |
| Purity | ≥95% (SDS-PAGE) |
| Formulation | Lyophilized from 20mM HEPES, pH 7.4. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Declaration | Manufactured by AbFrontier |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | After reconstitution, store at -80°C. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer’s disease.
Product References
1) Shoyab, M. et al (1986) J. Biol. Chem. 261: 11968-11973. (General)
2) Gray, P.W. et al (1986) Proc. Nat. Acad. Sci. 83:7547-7551. (General)
3) Ohkuma, S. et al (2001) Life Science 68: 1215-1222. (General)
2) Gray, P.W. et al (1986) Proc. Nat. Acad. Sci. 83:7547-7551. (General)
3) Ohkuma, S. et al (2001) Life Science 68: 1215-1222. (General)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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