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Adipogen/Di-ubiquitin [Ub2] Non-hydrolyzable (K63-linked) (human) (rec.) (Agarose)/AG-40T-0250-R250/250 µl
![Adipogen/Di-ubiquitin [Ub2] Non-hydrolyzable (K63-linked) (human) (rec.) (Agarose)/AG-40T-0250-R250/250 µl](https://www.ebiomall.cn/images/adipogen/adipogen_logo_bw_2.png)
Adipogen/Di-ubiquitin [Ub2] Non-hydrolyzable (K63-linked) (human) (rec.) (Agarose)/AG-40T-0250-R250/250 µl
商品编号:
AG-40T-0250-R250
品牌:
Adipogen Inc
市场价:
¥6980.00
美元价:
4188.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
ProductType | Protein |
Properties | |
Source/Host | E.coli |
Sequence | TwohumanubiquitinL73Pmutants(AccessionNr.P0CG47)covalentlylinkedthroughanisopeptidebondatK63residueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule,andcoupledtoagarose. |
Crossreactivity | Human |
Label/Conjugates | Agarose |
Formulation | Liquid.Resinsuppliedasa50%slurryin20%ethanol. |
OtherProductData | Use:Linkage-specific,non-hydrolyzabledi-ubiquitinisresistanttotheactivityofdeubiquitinatingenzymes(DUB"s)thatcleavetheisopeptidelinkagebetweenadjacentubiquitinmolecules.Maybeusefulforinvestigatingubiquitin-bindingproteinsandexploringtheroleofunanchored(freeC-terminus)ubiquitinchainsinsignalingpathways.Werecommendtoprepareresinbyrinsingwith10volumesofwatertoremoveethanolstoragebufferandequilibratingtheresinbywashingwith10volumesofyourdesiredaqueousbuffer. Polyubiquitin-agarosecanbere-usedifproperlymaintained.Afteruse,cleanresinwithawashcycleof5volumes100mMHEPESpH8.0,500mMNaClfollowedby5volumes100mMNaOAcpH4.5,500mMNaCl.Repeattwice,thenrinseresinwithalowsaltbuffer. |
Declaration | ManufacturedbyBostonBiochem |
ShippingandHandling | |
Shipping | BLUEICE |
ShortTermStorage | +4°C |
LongTermStorage | +4°C |
HandlingAdvice | Donotfreeze. |
Use/StABIlity | Stableforatleast3monthsafterreceiptwhenstoredat+4°C. |
Documents | |
MSDS | No |
ProductSpecificationSheet | |
Datasheet | ![]() |
Withapredictedmolecularweightof17kDa,di-ubiquitiniscomposedoftwoubiquitinmonomersthatarecovalentlylinkedthroughanisopeptidebond,whichtypicallyformbetweenalysineresidueofoneubiquitinmoleculeandtheC-terminalglycineresidueofanotherubiquitinmolecule.Eachhumanubiquitinmonomeris76aminoacids(aa)inlengthandshares96%and100%aaidentitywithyeastandmouseubiquitin,respectively.Ubiquitinhassevenlysineresiduesthatcanparticipateintheformationofpoly-ubiquitinchains.Thespecificlysineresidueusedinubiquitinconjugationisthoughttodeterminethefunctionofpoly-ubiquitinationincellularprocessessuchasproteindegradation,signalingandtrafficking.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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