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Adipogen/COMP (rat):Angiopoietin-1 (human) (rec.)/AG-40B-0147-C010/10 µg
Adipogen/COMP (rat):Angiopoietin-1 (human) (rec.)/AG-40B-0147-C010/10 µg
商品编号：
AG-40B-0147-C010
品牌：
Adipogen Inc
市场价：
¥4000.00
美元价：
2400.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | COMP-Ang1; COMP:Ang-1; COMP Angiopoietin 1; COMP ANGPT1 |
| Product Type | Protein |
| Properties | |
| Source/Host | CHO cells |
| Sequence | The fibrinogen-like domain (aa 284-498) of human angiopoietin-1 is fused at the N-terminus to the coiled-coil domain of rat COMP (cartilage oligomeric matrix protein) and to a FLAG®-tag. |
| Crossreactivity | Human |
| Specificity | Binds to human angiopoietin-1 receptor (Tie-2). |
| Biological Activity | More potent than native angiopoietin-1. The protein forms pentameric structures. |
| MW | 35kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.05eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration |
After reconstitution: for 10µg size: 0.1mg/ml for 50µg size: 1 mg/ml |
| Reconstitution |
10µg size: Reconstitute with 100µl sterile water. 50µg size: Reconstitute with 50µl sterile water. |
| Formulation | Lyophilized. Contains PBS + 0.02% CHAPS. |
| Other Product Data |
UniProt link Q15389: Angiopoietin-1 (human) UniProt link P35444: COMP (rat) FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Soluble, stable and more potent angiopoietin-1 (Ang-1) variant.
Product References
- COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity: CH. Cho, et al.; PNAS 101, 5547 (2004)
- COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model: CH. Cho, et al.; PNAS 103, 4946 (2006)
- Protective role of COMP-Ang1 in ischemic rat brain: HY. Shin, et al.; J. Neurosci. Res. 88, 1052 (2010)
- COMP-angiopoietin-1 promotes cavernous angiogenesis in a type 2 diabetic rat model: SO. Kim, et al.; J. Korean Med. Sci. 28, 725 (2013)
- COMP-Ang1 accelerates chondrocyte maturation by decreasing HO-1 expression: S. Kim, et al.; J. Cell. Biochem. 114, 2513 (2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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