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Adipogen/CD273 [PD-L2] (mouse):Fc (mouse) (rec.)/CHI-MF-110PDL2-C100/100 µg
![Adipogen/CD273 [PD-L2] (mouse):Fc (mouse) (rec.)/CHI-MF-110PDL2-C100/100 µg](https://www.ebiomall.cn/images/adipogen/adipogen_logo_bw_2.png){kind=logo}
Adipogen/CD273 [PD-L2] (mouse):Fc (mouse) (rec.)/CHI-MF-110PDL2-C100/100 µg
商品编号：
CHI-MF-110PDL2-C100
品牌：
Adipogen Inc
市场价：
¥6400.00
美元价：
3840.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ProgrammedCellDeath1Ligand2;PDCD1Ligand2;B7-DC;PDL2 |
| ProductType | Protein |
| Properties | |
| Source/Host | CHOcells |
| Sequence | TheextracellulardomainofmouseCD273[PD-L2](aa20-219)isfusedtotheN-terminusoftheFcregionofmouseIgG2a. |
| Crossreactivity | Mouse |
| Purity | ≥98%(SDS-PAGE) |
| EndotoxinContent | <0.06eu mu;g="" protein="" (lal="" test;="" lonza).=""> |
| Reconstitution | Reconstituteat100μg/mlinsterilePBS. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceNP_067371.1:CD273(mouse) |
| Declaration | ManufacturedbyChimerigen. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
TcellsrequireasignalinducedbytheengagementoftheTcellreceptorandacostimulatorysignal(s)throughdistinctTcellsurfacemoleculesforoptimalTcellactivationandtolerance.CD273(PD-L2)isoneoftwoligandsforprogrammeddeath-1(PD-1;CD279),amemberoftheCD28familyofimmunoreceptors.TheotheridentifiedligandisPD-L1.CD273isbroadlyexpressedandalsoupregulatedinavarietyoftumorcelllines.OnpreviouslyactivatedTcells,CD273interactionwithPD-1inhibitsTCRmediatedproliferationandcytokineproduction,suggestinganinhibitoryroleinregulatingimmuneresponses.CD273hasacostimulatoryfunctiononrestingTcellsactivatedwithsuboptimalTCRsignals.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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