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Adipogen/CD1D (human):Fc (human) (rec.)/CHI-HF-210CD1D-C050/50 µg
Adipogen/CD1D (human):Fc (human) (rec.)/CHI-HF-210CD1D-C050/50 µg
商品编号:
CHI-HF-210CD1D-C050
品牌:
Adipogen Inc
市场价:
¥5800.00
美元价:
3480.00
产品分类:
其它重组蛋白
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | R3G1 |
| ProductType | Protein |
| Properties | |
| Source/Host | HEK293cells |
| Sequence | TheextracellulardomainofhumanCD1D[R3G1](aa20-301)isfusedtotheN-terminusoftheFcregionofhumanIgG1. |
| Crossreactivity | Human |
| MW | ~75kDa |
| Purity | ≥98%(SDS-PAGE) |
| EndotoxinContent | <5eu g="" protein="" (lal="" test;="" lonza).="">5eu> |
| Reconstitution | Reconstituteat1mg/mlinsterilewater. Add1XPBStothedesiredproteinconcentration. |
| Formulation | Lyophilizedfrom0.2μm-filteredsolutioninPBS. |
| OtherProductData | NCBIreferenceAAH27926.1:CD1D(human) |
| Declaration | ManufacturedbyChimerigen. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
HumanT-cellsurfaceglycoproteinCD1d,asknownasR3G1,isanon-polymorphicMHC-likemoleculewhichcontainsoneIg-like(immunoglobulin-like)domain,shares65%and68%aasequenceidentitywithmouseandratCD1D,respectively.TheCD1familyofantigenpresentingmoleculesconsistsoffivemembers,CD1A,CD1B,CD1C,CD1D,andCD1E.CD1Disexpressedoncorticalthymocytes,oncertainT-cellleukemias,andinvariousothertissues.Itishighlyexpressedinpremalignantandearlymyeloma,withdiseaseprogressionitsexpressionisreducedandeventuallyinadvancedstagesandmyelomacelllinesislostaltogether,suggestingthatCD1Dimpactsnegativelyonmyelomacellsurvival.HumanCD1Dmoleculesbindasurprisingdiversityoflipidstructureswithinthesecretorypathway,includingcompoundsthathavebeenreportedtoplayrolesincancer,autoimmunediseases,lipidsignaling,andcelldeath.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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