脂肪原/ATG7亚型1（人类）（记录）（His）/AG-40T-0227-C050/50µg
商品编号：
AG-40T-0227-C050
品牌：
Adipogen Inc
市场价：
¥9720.00
美元价：
5832.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | AutophagyRelated7Homolog;APG7;APG7L;GSA7;Ubiquitin-likeModifier-activatingEnzymeATG7;ATG12-activatingEnzymeE1 |
| ProductType | Protein |
| Properties | |
| Source/Host | Sf21cells |
| Sequence | HumanATG7Isoform1(AccessionNr.O95352-1)fusedtoaN-terminalHis-tag. |
| Crossreactivity | Human |
| Formulation | Liquid.InHEPES,NaCl,TCEPandGlycerol. |
| OtherProductData | Use:MemberoftheApg-activating(E1)enzymefamilythatisrequiredforthefirststepoftheenzymaticcascadethatsubsequentlyutilizesaApg-conjugating(E2)enzymeandaApgligase(E3)toconjugateApgtosubstrateproteins.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof50-200nM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
ATG7,alsoknownasAPG7,isa78kDacytosolicubiquitinE1-likeenzymethatplaysakeyroleintheautophagypathwayofintracellularbulkdegradation.ItisrequiredfortheconjugationofATG5toATG12,thelipidationofATG8proteinsincludingGABARAP,GABARAPL1,GABARAPL2orMAP1LC3A,andthesubsequentformationofautophagosomes.ATG7isrequiredformitochondrialremovalduringerythropoiesis(“mitophagy”)andforthemaintenanceofaxonalhomeostasis.AlternatesplicingofhumanATG7generatesanisoformthatlacks31aaattheC-terminus,aregionthatisrequiredforATG8lipidation.HumanATG7shares93%aasequenceidentitywithmouseandratATG7.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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