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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/Ataxin (UIM domains) (human) (rec.) (Agarose)/AG-40T-0221-R250/250 µl
商品详细Adipogen/Ataxin (UIM domains) (human) (rec.) (Agarose)/AG-40T-0221-R250/250 µl
Adipogen/Ataxin (UIM domains) (human) (rec.) (Agarose)/AG-40T-0221-R250/250 µl
Adipogen/Ataxin (UIM domains) (human) (rec.) (Agarose)/AG-40T-0221-R250/250 µl
商品编号: AG-40T-0221-R250
品牌: Adipogen Inc
市场价: ¥6980.00
美元价: 4188.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsAtaxin-3;Machado-JosephDiseaseProtein1;SpinocerebellarAtaxiaType3Protein;ATXN3;ATX3,MJD,MJD1,SCA3
ProductTypeProtein
Properties
Source/HostE.coli
SequenceHumanataxin(UIMdomainsaa224-348)(AccessionNr.P54252-1)isconjugatedtoagarose.
CrossreactivityHuman
Label/ConjugatesAgarose
FormulationLiquid.In50mMHEPES,pH7.5,250mMNaCl.
OtherProductDataUse:Thisaffinityresincanbeusedfortheenrichment,isolationandidentificationofK48-linked(preferentially)orK63-linkedpoly-ubiquitinchainsorubiquitinatedsubstratesthatcontaintheselinkages.Equilibrateresinbywashingwith5-10mldesiredstartbuffer.

Storage:Theagarosecanbere-usedforatleast2applicationsifproperlymaintained.Afteruse,cleanresinwith5ml50mMTrispH9.0,1MKCl.Removecleaningsolutionbywashingresinwith5mlstoragebuffer.
DeclarationManufacturedbyBostonBiochem
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage+4°C
HandlingAdviceDonotfreeze.
Use/StABIlityStableforatleast3monthsafterreceiptwhenstoredat+4°C.
Documents
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
Theubiquitin-interactingmotif(UIM)isanα-helicalubiquitin-bindingdomainfoundinmanyproteinsthatrecognizesandtrafficsubiquitinatedcargo.Ataxin-3,adeubiquitinatingenzymethatcontainsthreeconsecutiveUIMmotifs(aminoacids(aa)224-243,244-263,331-348),functionsasamixedlineage,chaineditingenzymethatrecognizesandbindsK48-linkedandK63-linkedpoly-ubiquitinchains.TheUIMdomainofataxin-3(aa224-348)preferentiallyinteractswithfourormoreubiquitinunitsofK48-linkedorK63-linkedpoly-ubiquitinchainsorubiquitinatedsubstratesthatcontaintheselinkages.
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。