当前位置：
首页
>
产品中心 >
Other_recombinant_protein >
Adipogen/ANGPTL4 (mouse) (rec.)/AG-40A-0075-C010/10 µg
Adipogen/ANGPTL4 (mouse) (rec.)/AG-40A-0075-C010/10 µg
商品编号：
AG-40A-0075-C010
品牌：
Adipogen Inc
市场价：
¥3200.00
美元价：
1920.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Angiopoietin-likeProtein4;FIAF;Fasting-inducedADIposeFactor;HFARP;HepaticFibrinogen/Angiopoietin-relatedProtein |
| ProductType | Protein |
| Properties | |
| Source/Host | COS-7cells |
| Sequence | MouseANGPTL4(aa1-410)isfusedattheC-terminustoaFLAG®-tag. |
| Crossreactivity | Mouse |
| BIOLOGicalActivity | ActivatesERKphosphorylationinTHP-1cells. |
| MW | ~50kDa(SDS-PAGE) |
| Purity | ≥90%(SDS-PAGE) |
| EndotoxinContent | <0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).=""> |
| Concentration | 1mg/ml |
| Formulation | Liquid.0.2μm-filteredsolutioninPBS. |
| OtherProductData | UniProtlinkQ9Z1P8:ANGPTL4(mouse)[Precursor] FLAGisaregisteredtrademarkofSigma-AldrichCo. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. |
| Use/StABIlity | Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
ANGPTL4(Angiopoietin-likeprotein4)mainlyexpressedinendothelialcells(hypoxia-induced).RegulatesangiogenesisandmodulatestumOrigenesisanddirectlyregulateslipid,glucose,andenergymetabolism.Inhibitsproliferation,migration,andtubuleformationofendothelialcellsandreducesvascularleakage.ANGPTL4isaproteinconsistingofanN-terminalcoiled-coildomainandaC-terminalfibrinogen-likedomain(FLD).Bothdomainshavedistinctbiologicalfunctions.Thecoiled-coildomainisresponsIBLefortheinhibitoryeffectsonlipoproteinlipase(LPL)convertingtheactiveformofLPLintoaninactiveform,andtheFLDdomainmediatesitsantiangiogenicfunctions.ThecoiledcoilandtheFLDdomainsareseparatedbyashortlinkerthatcanbecleavedaftersecretion.ANGPTL4appearsonthecellsurfaceasthefull-lengthform,whereitcanbereleasedbyheparintreatment.ANGPTL4proteinisthenproteolyticallycleavedbyproproteinconvertases(PCs),includingfurin,PC5/6,pairedbasicaminoacid-cleavingenzyme4,andPC7.
ProductReferences
- RegulationofenergybalancebythehypothalamiclipoproteinlipaseregulatorAngptl3:H.K.Kim,etal.;Diabetes64,1142(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
